Winston Timp

Winston Timp, Ph.D.

  • Position:
    Post Doctoral Fellow

    Medicine

    Johns Hopkins School of Medicine (Baltimore, MD)

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  • Advisors:

    Andrew P Feinberg, Andre Levchenko

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  • Degrees:
     
    Ph.D., Electrical Engineering, Massachusetts Institute of Technology (Cambridge, MA)
     
    M.Sc., Electrical Engineering, Massachusetts Institute of Technology (Cambridge, MA)
     
    B.Sc., Biochemistry, University of Illinois at Urbana-Champaign (Urbana, IL)
     
    B.Sc., Physics, University of Illinois at Urbana-Champaign (Urbana, IL)
     
    B.Sc., Chemistry, University of Illinois at Urbana-Champaign (Urbana, IL)
     
    B.Sc., Electrical Engineering, University of Illinois at Urbana-Champaign (Urbana, IL)
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  • Past Advisors:
     
    Paul Matsudaira (as Graduate Student - Ph.D.)
     
    Joe Lyding (as Undergraduate Student)
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  • Research:
    Studying epigenetic effects on cancer from the organism level(human samples, animal models) to the cellular level(in vitro assays, microfluidics) and down to the single molecule level(nanopore-based force measurement, biochemical assays).

    My recent work has been focussed on studying the epigenetic changes occuring in cancer. I have examined the methylation profile of different cancer samples, with an angle towards understanding and identifying changes which occur in DNA methylation profiles. I have worked on characterizing the byplay between cell-signaling and epigenetics, studying both the epithelial-mesenchymal transition and loss-of-imprinting of IGF2. I also have examined the effects of DNA methylation on the DNA molecule itself, finding that epigenetic modifications have ramifications for biophysical properties.

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  • Other Experience:

    1998 Bell Laboratories, Lucent Technologies

    1997 Bell Laboratories, Lucent Technologies

    1996 Bell Laboratories, Lucent Technologies

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  • Honors:

    2010-present Ruth L. Kirschstein National Research Service Awards For Individual Postdoctoral Fellows (F32)

    2008 Young Investigator Award - American Academy of Nanomedicine

Life Sciences
Communities:

Winston Timp's Genealogy

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Winston Timp's Publications (14)



Winston Timp's Posters and Presentations (9)

  • Epigenetics for Risk Prevention (presentation)

    Winston Timp

    Predictive genetic diagnostics as an instrument for disease prevention, Leopoldina Conference; 02/2010
  • Study of Cell-Cell Communication Using Optically Assembled 3D Living Cell Microarrays. (presentation)

    Winston Timp, Utkur Mirsaidov, K. Timp, G. Timp, P. Matsudaira

    Micro Total Analysis Systems 2008; 10/2008
  • 3D Living Cell Microarrays Assembled Using Optical Tweezers. (presentation)

    Winston Timp, Utkur Mirsaidov, K. Timp, G. Timp, P. Matsudaira

    Synthetic Biology 3.0; 06/2007
  • Laser-Guided Assembly of 3D Living Cell Microarrays. (poster)

    Winston Timp, U. Mirsaidov, K. Timp, G. Timp, P. Matsudaira

    American Academy of Nanomedicine, Best Poster; 09/2006
  • Tools to investigate cell-cell communication. (presentation)

    Winston Timp

    Whitehead Forum; 03/2006
  • Laser-Guided Assembly of 3D Living Cell Microarrays. (presentation)

    Winston Timp, G. M. Akselrod, C. Li, K. Timp, R. Timp, Q. Zhao, G. Timp, P. Matsudaira

    Biophysical Society; 02/2006
  • Statistical Analysis of Phototoxic Effects of Fluorescent Markers on Cell Motility (poster)

    Winston Timp, S. Hopp, J. G. Evans, and P. Matsudaira

    American Society of Cell Biology; 12/2005
  • Wet Electron Microscopy Using Quantum Dots. (poster)

    Winston Timp, N. Watson, A. Sabban, O. Zik, P. Matsudaira

    American Society of Cell Biology; 12/2005
  • Two-dimensional dopant profiling of a 60 nm gate length nMOSFET using scanning capacitance microscopy. (presentation)

    Winston Timp, M. L. O'Malley, R. N. Kleiman, and J. P. Garno.

    IEDM; 12/1998

One Figure

One Figure for Winston Timp

Pictured is a multidimensional scaling of DNA methylation for different tissues and corresponding cancer samples. Normal samples are distinguished from each other, but show a distinct profile(dotted ellipse). Cancer samples are much more variable.


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