Valmik K. Vyas

Valmik K. Vyas, Ph.D.

  • Position:
    Post Doctoral Fellow

    Fink Lab

    Whitehead Institute for Biomedical Research (Cambridge, MA)

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  • Advisor:

    Gerald R. Fink

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  • Degrees:
     
    Ph.D., Cellular, Molecular, & Biophysical Studies, Columbia University (New York, NY)
     
    M.Phil., Cellular, Molecular, & Biophysical Studies, Columbia University (New York, NY)
     
    M.A., Cellular, Molecular, & Biophysical Studies, Columbia University (New York, NY)
     
    S.B., Biology, Massachusetts Institute of Technology (Cambridge, MA)
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  • Past Advisors:
     
    Marian B. Carlson (as Post Doctoral Fellow)
     
    Marian B. Carlson (as Graduate Student - Ph.D.)
     
    Peter Sorger (as Undergraduate Student)
     
    Paul Matsudaira (as Undergraduate Student)
     
    Leonard P. Guarente (as Undergraduate Student)
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  • Research:
    I study the interaction of the fungal pathogen Candida alibicans with cells of the innate immune system.

    Candida albicans, the most frequently isolated human fungal pathogen, has developed several mechanisms to evade immune detection and killing. First, Candida is able to mask immunogens in its cell wall. Second, upon phagocytosis by macrophages, Candida is able to undergo hyphal morphogenesis. These filamentous cells are able to pierce through the macrophage and release the fungus to infect other tissues. I am using knockout and shRNA libraries to identify mutants of both the fungus and the host which alter this interaction.

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  • Other Experience:

    2008-present Co-Chairman, Whitehead Institute Postdoctoral Association

    2005-2007 Co-Director, Whitehead Forum

    1997 Biochemist, Merck Research Labs

    1996 Merck Research Labs

    1995 Schering Plough Research Institute

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  • Honors:

    2007-2010 Ruth L. Kirschstein National Research Service Award

    2006 Herman and Margaret Sokol Postdoctoral Fellowship

    2004 Dissertation with Distinction (Ph.D.), Columbia University

    1993-1996 AFL-CIO Scholar

    1993-1996 Robert C. Byrd Scholar

    1993-1996 NHS Scholar

    1993 Panasonic Creative Design Competition, 2nd Place

    1993 Valedictorian, West Orange High School, West Orange, NJ

Life Sciences
Communities:

Valmik Vyas's Genealogy

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Valmik Vyas's Publications (9)



One Figure

One Figure for Valmik K. Vyas

Phagocytosis of Candida by human macrophages or monocytes (A) induces filamentation, whereas phagocytosis by neutrophils (B) does not. From Rubin-Bejerano, et al. http://www.pnas.org/cgi/content/ful...


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