Epernicus: Utpal B Pajvani, M.D., Ph.D.

Utpal B Pajvani, M.D., Ph.D.

Position:
Clinical Fellow

Endocrinology

Columbia University Medical Center (New York, NY)
Advisor:
Domenico Accili
Degrees:

M.D., Albert Einstein College of Medicine (Bronx, New York)

Ph.D., Cell Biology, Albert Einstein College of Medicine (Bronx, New York)

M.S., Cell Biology, Albert Einstein College of Medicine (Bronx, New York)

S.B., Biology, Massachusetts Institute of Technology (Cambridge, MA)
Clinical Training:

Fellowship (in progress), Endocrinology, Columbia Presbyterian Medical Center

Residency, Internal Medicine, Columbia Presbyterian Medical Center
Past Advisors:

Philipp Scherer (as Graduate Student - Ph.D.)

Anthony J. Sinskey (as Undergraduate Student)

Robert S Langer (as Undergraduate Student)
Research:
Other Experience:
2006 Summer Intern, Merck

2005 Summer Intern, Schering-Plough Research Institute
Honors:
2005 Alpha Omega Alpha

2005 Julius Marmur Research Symposium Award

1997 Sigma Xi Scientific Research Society Award

1993 Rensselaer Medal for Excellence in Math and Science

1993 White House Presidential Scholar’s Award

Communities:

Utpal Pajvani's Genealogy

The Adobe Flash Player plugin (version 8) is required to view the genealogy tree.
Download the plugin here.

Utpal Pajvani's Publications (16)

Selective downregulation of the high molecular weight form of adiponectin in hyperinsulinemia and in type 2 diabetes: differential regulation from nondiabetic subjects.
Basu R, Pajvani UB, Rizza RA, Scherer PE

Diabetes. 2007 Aug;56(8):2174-7
Mice lacking adiponectin show decreased hepatic insulin sensitivity and reduced responsiveness to peroxisome proliferator-activated receptor gamma agonists.
Nawrocki AR, Rajala MW, Tomas E, Pajvani UB, Saha AK, Trumbauer ME, Pang Z, Chen AS, Ruderman NB, Chen H, Rossetti L, Scherer PE

The Journal of biological chemistry. 2006 Feb 3;281(5):2654-60
Apoptosis through targeted activation of caspase 8 ("ATTAC-mice"): novel mouse models of inducible and reversible tissue ablation.
Trujillo ME, Pajvani UB, Scherer PE

Cell cycle (Georgetown, Tex.). 2005 Sep;4(9):1141-5
Fat apoptosis through targeted activation of caspase 8: a new mouse model of inducible and reversible lipoatrophy.
Pajvani UB, Trujillo ME, Combs TP, Iyengar P, Jelicks L, Roth KA, Kitsis RN, Scherer PE

Nature medicine. 2005 Jul;11(7):797-803
Adiponectin: a relevant player in PPARgamma-agonist-mediated improvements in hepatic insulin sensitivity?
Bouskila M, Pajvani UB, Scherer PE

International journal of obesity (2005). 2005 Mar;29 Suppl 1:S17-23
Thiazolidinediones improve insulin sensitivity in adipose tissue and reduce the hyperlipidaemia without affecting the hyperglycaemia in a transgenic model of type 2 diabetes.
Kim H, Haluzik M, Gavrilova O, Yakar S, Portas J, Sun H, Pajvani UB, Scherer PE, LeRoith D

Diabetologia. 2004 Dec;47(12):2215-25
Regulation of resistin expression and circulating levels in obesity, diabetes, and fasting.
Rajala MW, Qi Y, Patel HR, Takahashi N, Banerjee R, Pajvani UB, Sinha MK, Gingerich RL, Scherer PE, Ahima RS

Diabetes. 2004 Jul;53(7):1671-9
Mechanisms of early insulin-sensitizing effects of thiazolidinediones in type 2 diabetes.
Tonelli J, Li W, Kishore P, Pajvani UB, Kwon E, Weaver C, Scherer PE, Hawkins M

Diabetes. 2004 Jun;53(6):1621-9
Adiponectin acts in the brain to decrease body weight.
Qi Y, Takahashi N, Hileman SM, Patel HR, Berg AH, Pajvani UB, Scherer PE, Ahima RS

Nature medicine. 2004 May;10(5):524-9
Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity.
Pajvani UB, Hawkins M, Combs TP, Rajala MW, Doebber T, Berger JP, Wagner JA, Wu M, Knopps A, Xiang AH, Utzschneider KM, Kahn SE, Olefsky JM, Buchanan TA, Scherer PE

The Journal of biological chemistry. 2004 Mar 26;279(13):12152-62
A transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivity.
Combs TP, Pajvani UB, Berg AH, Lin Y, Jelicks LA, Laplante M, Nawrocki AR, Rajala MW, Parlow AF, Cheeseboro L, Ding YY, Russell RG, Lindemann D, Hartley A, Baker GR, Obici S, Deshaies Y, Ludgate M, Rossetti L, Scherer PE

Endocrinology. 2004 Jan;145(1):367-83
Adiponectin: systemic contributor to insulin sensitivity.
Pajvani UB, Scherer PE

Current diabetes reports. 2003 Jun;3(3):207-13
Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin. Implications fpr metabolic regulation and bioactivity.
Pajvani UB, Du X, Combs TP, Berg AH, Rajala MW, Schulthess T, Engel J, Brownlee M, Scherer PE

The Journal of biological chemistry. 2003 Mar 14;278(11):9073-85
Differential glycosylation of interleukin 2, the molecular basis for the NOD Idd3 type 1 diabetes gene?
Podolin PL, Wilusz MB, Cubbon RM, Pajvani U, Lord CJ, Todd JA, Peterson LB, Wicker LS, Lyons PA

Cytokine. 2000 May;12(5):477-82
Colorimetric analysis of surface reactive amino groups on poly(lactic acid-co-lysine):poly(lactic acid) blends.
Cook AD, Pajvani UB, Hrkach JS, Cannizzaro SM, Langer R

Biomaterials. 1997 Nov;18(21):1417-24
Characterization and development of RGD-peptide-modified poly(lactic acid-co-lysine) as an interactive, resorbable biomaterial.
Cook AD, Hrkach JS, Gao NN, Johnson IM, Pajvani UB, Cannizzaro SM, Langer R

Journal of biomedical materials research. 1997 Jun 15;35(4):513-23

Utpal Pajvani's Posters and Presentations (1)

Interaction between Foxo and Notch proteins in differentiation and hormonal regulation (poster)
Utpal B Pajvani

Keystone Symposium on Diabetes Mellitus and Insulin Resistance; 01/2008

Join Epernicus (membership is free)

Epernicus is open to current and former research scientists.

Already a member?
Sign in to view Utpal's full profile.

Utpal B Pajvani, M.D., Ph.D.

Clinical Fellow

Utpal Pajvani's Genealogy

Utpal Pajvani's Publications (16)

Utpal Pajvani's Posters and Presentations (1)