
Center for Gene Regulation in Health and Disease
Cleveland State University (Cleveland, OH)
Eukaryotic ribosomal protein S5 belongs to a family of ribosomal proteins that includes bacterial rpS7. rpS5/rpS7 forms part of the exit (E) site on the small ribosomal subunit and cross-links to the E-site tRNA. rpS7 also contributes to the formation of the mRNA exit channel and interacts with rpS11, which is located on the platform of the 30S subunit. E. coli rpS7 initiates assembly of the 30S subunit by binding to 16S rRNA.


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