Epernicus: Surendra S Ambegaokar, B.A.

Surendra S Ambegaokar, B.A.

(Ph.D. in progress)

Position:
Graduate Student - Ph.D.

Neuroscience

Neurology

University of California, Los Angeles (Los Angeles, CA)
Advisor:
George R Jackson
Degrees:

Ph.D. (in progress), Neuroscience, University of California, Los Angeles (Los Angeles, CA)

B.A., Molecular & Cell Biology: Neurobiology, University of California, Berkeley (Berkeley, CA)
Past Advisors:

Greg M. Cole (as Technician)

Paola Timiras (as Undergraduate Student)

Wayne van Deusen (as Undergraduate Student)
Research:
screen for genetic modifiers of tauopathy
Other Experience:
2007 Summer Course in Molecular Neurology and Neuropathology
Honors:
2006-2008 NIH-UCLA Predoctoral Fellow, Neurobehavioral Genetics

2005-2006 NIH-UCLA Predoctoral Fellow, Neural Repair

Communities:

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Antibodies against beta-amyloid reduce Abeta oligomers, glycogen synthase kinase-3beta activation and tau phosphorylation in vivo and in vitro.
Ma QL, Lim GP, Harris-White ME, Yang F, Ambegaokar SS, Ubeda OJ, Glabe CG, Teter B, Frautschy SA, Cole GM

Journal of neuroscience research. 2006 Feb 15;83(3):374-84
Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo.
Yang F, Lim GP, Begum AN, Ubeda OJ, Simmons MR, Ambegaokar SS, Chen PP, Kayed R, Glabe CG, Frautschy SA, Cole GM

The Journal of biological chemistry. 2005 Feb 18;280(7):5892-901
Insulin-degrading enzyme as a downstream target of insulin receptor signaling cascade: implications for Alzheimer's disease intervention.
Zhao L, Teter B, Morihara T, Lim GP, Ambegaokar SS, Ubeda OJ, Frautschy SA, Cole GM

The Journal of neuroscience : the official journal of the Society for Neuroscience. 2004 Dec 8;24(49):11120-6
Curcumin inhibits dose-dependently and time-dependently neuroglial cell proliferation and growth.
Ambegaokar SS, Wu L, Alamshahi K, Lau J, Jazayeri L, Chan S, Khanna P, Hsieh E, Timiras PS

Neuro endocrinology letters. 2003 Dec;24(6):469-73

An in vivo genetic loss-of-function modifier screen in a Drosophila model of tauopathy (poster)
Ambegaokar SS, Wang X-F, Jackson GR

Society for Neuroscience; 11/2008
Curcumin inhibits dose-dependently neuroglial cell proliferation and growth (poster)
Ambegaokar SS, Jazayeri L, Alamshahi K, Wu L, and Timiras PS

Federation of American Societies for Experimental Biology; 06/2003
4.1R knockout mice a model of chronic disease: Chronic physiological stress, elevated corticosterone, and hippocampal damage (poster)
Ambegaokar SS, van Deusen WJ, Gascard PD, and Saatman KE

Society for Neuroscience; 11/2002
Changes in the dentate gyrus (DG) in knock-out transgenic sickle cell mice (KTSCM) caused by chronic stress (poster)
Ambegaokar SS, van Deusen WJ, Timiras PS, and Rosenzweig M

Society for Neuroscience; 11/2001

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