Stephanie R Dukovcic

Stephanie R Dukovcic, Ph.D.

  • Position:
    Post Doctoral Scholar

    Nutrition & Exercise Science

    Oregon State University (Corvallis, OR)

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  • Advisor:

    Emily Ho

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  • Degrees:
     
    Ph.D., Microbiology, Oregon State University (Corvallis, OR)
     
    B.Sc., Bioengineering, Oregon State University (Corvallis, OR)
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  • Past Advisors:
     
    Janine E. Trempy (as Graduate Student - Ph.D.)
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  • Research:
    For my graduate work I studied a cell-based biosensor isolated from Betta splendens as a detector for Salmonella typhimurium and other Gram negative foodborne pathogens.

    Cell-based biosensors are viable eukaryotic cells that report the presence of toxicants of chemical or biological origin. These sensors possess an innate feature that can be exploited to detect toxic substances and much research has gone into optimizing cell-based biosensors for food- and water-based analyses. Chromatophores have emerged as an intriguing class of cell-based biosensors that respond to contaminants based on a function dependent mechanism, rather than the structure-based approach associated with PCR and ELISA. We have identified at least one underlying mechanism of the B. splendens erythrophore cell-based biosensor response to Salmonella typhimurium and it is directly related to the invasive potential of S. typhimurium.

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  • Honors:

    2008-2009 Supplemental Oregon Laurels Graduate Scholarship

    2008-2009 Oregon Lottery Graduate Scholarship

    2007-2009 Oregon Department of Fish and Wildlife Predoctoral Fellowship

    2007 Harriet M. Winton Graduate Scholarship

    2006 Middlekauf Outstanding Graduate Teaching and Service Scholarship

    2006 National Science Foundation Graduate Research Fellowship Honorable Mention

Life Sciences
Communities:

Stephanie Dukovcic's Genealogy

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Stephanie Dukovcic's Publications (2)



Stephanie Dukovcic's Posters and Presentations (3)

  • Chromatophores as Cell-based Biosensors for the Detection of Chemically and Biologically Toxic Substances (presentation)

    Stephanie R Dukovcic

    Oregon State University, PhD Dissertation Defense; 09/2009
  • Biosensor Response to Pathogenic Bacteria (poster)

    Janine R Hutchison, Melissa J Austin, Ryan Smith, Stephanie R Dukovcic, Bruce A Caldwell, Janine E Trempy

    American Soceity for Microbiology, National Conference, Orlando FL; 05/2006
  • Assessment of Bacterial Toxicity in Northwest Fish Hatcheries (poster)

    Stephanie R Dukovcic, Bruce A Caldwell, Janine E Trempy

    American Soceity for Microbiology, Northwest Regional Meeting, Seattle WA; 03/2006

One Figure

One Figure for Stephanie R Dukovcic

Salmonella typhimurium SPI1 T3SS apparatus. The SPI1 T3SS consists of the needle like apparatus and the translocon, formed primarily by structural proteins prgHIJK and SipBCD respectively. This T3SS plays a major role in erythrophore aggregation.


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