Silke Paust

Silke Paust, Ph.D.

  • Positions:
    Post Doctoral Fellow (2005-ongoing)

    Pathology

    Harvard Medical School (Boston, MA)

    Fellowship recipient (2007-2009)

    Irvington Institute Fellowship Program of the Cancer Research Institute (New York, NY)

    Post Doctoral Fellow (2010-2011)

    The Ragon Institute of MGH, MIT and Harvard

  •  
  • Advisor:

    Ulrich H. von Andrian

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  • Degrees:
     
    Ph.D., Immunology, Harvard Medical School (Boston, MA)
     
    M.S., Biomedical Sciences , Washington University School of Medicine (St. Louis, MO)
     
    B.Sc., Biochemistry, University of Wisconsin-Madison (Madison, WI)
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  • Past Advisors:
     
    Harvey I Cantor (as Graduate Student - Ph.D.)
     
    Matthew L. Thomas (as Graduate Student - Masters)
     
    Garry Spitter (as Undergraduate Student)
  •  
  • Research:
    PhD Immunologist with extensive experience in mouse models of autoimmune and allergic disease, cellular and molecular immunology, cell biology and biochemistry.

    Extensive knowledge of T, regulatory T, B and NK cell biology and their contributions to immunity or immunological disorders. Extensive experience with mouse models of Multiple Sclerosis, Inflammatory Bowel Disease and Herpes Stromal Keratitis.

    Experienced at supervising high school student volunteers, undergraduate students, graduate students and laboratory technicians. Teaching assistant to several graduate level immunology courses.

    Successful fellowship writing, manuscript preparation, and manuscript review for peer reviewed journals.

    My work aims to better define different subsets of Natural Killer (NK) cells based on their ability to recognize and distinguish different antigens, and mount memory responses. NK cells are part of the human and mouse immune system, and have the ability to kill virally infected cells and cancer cells, but may also contribute to autoimmune diseases, making them attractive targets for therapeutic intervention. A better understanding of NK cell biology will aid therapeutic intervention of NK cell mediated diseases, and may lead to novel treatment options for patients of autoimmune disease, viral infections and cancers.

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  • Other Experience:

    2007-2008 Supervisor, Annette Hellbach, Science Internship. Annette s currently pursuing a PhD in Molecular Medicine at the University of Erlangen, Germany.

    2007 Supervisor, Kristine Xue, Science Internship for High School Seniors in collaboration with Boston Latin and the Immune Disease Institute, Boston, MA. Kristine is currently pursuing early admissions requirements for medical school at Boston University.

    2004 Teaching Assistant to Hidde Ploegh, Cold Spring Harbor, Watson School of Biology, “Topics in Immunology”.

    2003 Supervisor, Boston Latin School Minority Science Program for high school seniors in collaboration with the Dana Farber Cancer Institute

    2001-2003 Supervisor, David Shim, Harvard University; Senior Honor’s Thesis “Identification of the auto-antigen of Herpes Stromal Keratitis in Balb/c mice.” David is currently pursuing his MD/PhD degree in Baylor.

    2001-2003 Supervisor, Stacey Fernandes, Emmanuel College; Senior Honor’s Thesis “The role of IL-12 and RAG2 in the development of thyroid disease”. Stacey is currently a technician at the Immune Disease Institute, Boston, MA.

    1998-1999 Teaching Assistant, “Foundations in Immunology” graduate level, Washington University, St. Louis. MO.

    1995 Summer internship in Enzymology, BASF Ag, Ludwigshafen, Germany

    1994 Summer internship in Bacterial Genetics, BASF Ag, Ludwigshafen, Germany

    1993 Summer internship in Pharmacology, BASF Ag, Ludwigshafen, Germany

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  • Honors:

    2010-present Fellowship Recipient of The Ragon Institute of MGH, MIT and Harvard

    2008 Fellowship recipient of the NK and NKT Cell Biology Keystone Meeting.

    2007-2009 Recipient of the Irvington Institute's Fellowship of the Cancer Research Institute.

    2004 Recipient of the Hauser Award for outstanding achievement in scientific research and teaching throughout graduate school training from Harvard University.

Life Sciences
Communities:

Silke Paust's Genealogy

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Silke Paust's Publications (8)



Silke Paust's Posters and Presentations (7)

  • Critical role for CXCR6 in NK cell mediated adaptive immunity to haptens and viruses (presentation)

    Silke Paust

    12th Meeting of the Society for Natural Immunity & NK2010, Cavtat, Croatia; 09/2010
  • Critical role for CXCR6 in NK cell mediated adaptive immunity to haptens and viruses (presentation)

    Silke Paust

    HIV Vaccine Developmen (Keystone Symposia).; 01/2010
  • Critical role for CXCR6 in NK cell mediated adaptive immunity to haptens and viruses (presentation)

    Silke Paust

    39th International Meeting of the Japanese Society of Immunologists, Osaka, Japan.; 12/2009
  • “T and B cell Independent Adaptive Immune Responses Mediated by Natural Killer Cells”. (presentation)

    Silke Paust

    Keystone Conference; NK and NKT Cell Biology, Keystone, CO ; 02/2008
  • “Molecular Target of regulatory T cells: Engagement of B7 on Effector T cells Inhibits Expansion and Autoimmune Disease”. (presentation)

    Silke Paust

    Yale University, School of Medicine, Department of Allergy and Clinical Immunology Seminar Series , Yale University, CT; 06/2007
  • “Molecular Target of regulatory T cells: Engagement of B7 on Effector T cells Inhibits Expansion and Autoimmune Disease”. (presentation)

    Silke Paust

    Joint DFCI-BWH-JDC Immunology Seminar Series, Harvard Medical School, MA; 05/2004
  • “Molecular Target of regulatory T cells: Engagement of B7 on Effector T cells Inhibits Expansion and Autoimmune Disease”. (presentation)

    Silke Paust

    Harvard University Program in Immunology Retreat, Loon Mountain, N.H. ; 11/2003


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