Epernicus: Stevan N Djakovic, Ph.D.

Stevan N Djakovic, Ph.D.

Position:
Senior Research Associate

Molecular Oncology

Genentech, Inc. (South San Francisco, CA)
Advisor:
avi ashkenazi
Degrees:

Ph.D., Biology, University of California, San Diego (San Diego, CA)

B.S., Biology: Biochemistry and Cell Biology, University of California, San Diego (San Diego, CA)
Past Advisors:

Albert La Spada (as Post Doctoral Fellow)

Gentry N Patrick (as Graduate Student - Ph.D.)

Laurie G. Smith (as Research Associate)
Research:
An accomplished cell and molecular neuroscientist with an emphasis in neurological disease research

I am interested in deciphering cellular and molecular mechanisms of neuronal dysfunction in neurological diseases. Specifically I am interested in cellular degradation pathways (autophagy, ubiquitin proteasome) and how their normal function contributes to neuronal physiology and dysfunction is involved in disease.
Other Experience:
2011 Buck Institute Stem Cell Workshop
Honors:
2010-2011 Neuroplasticity of Aging Postdoctoral Fellow

2008-2010 Neuroplasticity of Aging Predoctoral Fellow

Communities:

Stevan Djakovic's Genealogy

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Stevan Djakovic's Publications (7)

An essential postsynaptic role for the ubiquitin proteasome system in slow homeostatic synaptic plasticity in cultured hippocampal neurons.
Jakawich SK, Neely RM, Djakovic SN, Patrick GN, Sutton MA

Neuroscience. 2010 Dec 29;171(4):1016-31
Regulation of the proteasome by neuronal activity and calcium/calmodulin-dependent protein kinase II.
Djakovic SN, Schwarz LA, Barylko B, DeMartino GN, Patrick GN

The Journal of biological chemistry. 2009 Sep 25;284(39):26655-65
Regulation of synaptic structure by ubiquitin C-terminal hydrolase L1.
Cartier AE, Djakovic SN, Salehi A, Wilson SM, Masliah E, Patrick GN

The Journal of neuroscience : the official journal of the Society for Neuroscience. 2009 Jun 17;29(24):7857-68
Mice lacking doublecortin and doublecortin-like kinase 2 display altered hippocampal neuronal maturation and spontaneous seizures.
Kerjan G, Koizumi H, Han EB, Dubé CM, Djakovic SN, Patrick GN, Baram TZ, Heinemann SF, Gleeson JG

Proceedings of the National Academy of Sciences of the United States of America. 2009 Apr 21;106(16):6766-71
Plasma membrane-associated SCAR complex subunits promote cortical F-actin accumulation and normal growth characteristics in Arabidopsis roots.
Dyachok J, Shao MR, Vaughn K, Bowling A, Facette M, Djakovic S, Clark L, Smith L

Molecular plant. 2008 Nov;1(6):990-1006
BRICK1/HSPC300 functions with SCAR and the ARP2/3 complex to regulate epidermal cell shape in Arabidopsis.
Djakovic S, Dyachok J, Burke M, Frank MJ, Smith LG

Development (Cambridge, England). 2006 Mar;133(6):1091-100
Activation of Arp2/3 complex-dependent actin polymerization by plant proteins distantly related to Scar/WAVE.
Frank M, Egile C, Dyachok J, Djakovic S, Nolasco M, Li R, Smith LG

Proceedings of the National Academy of Sciences of the United States of America. 2004 Nov 16;101(46):16379-84

Stevan Djakovic's Posters and Presentations (1)

Regulation of the proteasome by neuronal activity and CaMKII (poster)
Stevan N Djakovic

Society for Neuroscience, Chicago; 11/2009

One Figure

Dissociated primary rat hippocampal neuron infected with Green Fluorescent protein via Sindbis virus.

Websites

Genentech

Shared Documents

brain_lysis_protocol.pdf - Brain protein lysates protocol

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