Epernicus: Simon M Alberti, Ph.D.

Simon M Alberti, Ph.D.

Position:
Group Leader

Max Planck Institute for Molecular Cell Biology and Genetics (Dresden, Germany)
Degrees:

Ph.D., Biochemistry, Cell Biology, Rheinische Friedrich Wilhelms Universitat Bonn (Bonn, Germany)

M.Sc., Cell Physiology, Molecular Biology, University of Bochum (Bochum, Germany)
Past Advisors:

Susan Lindquist (as Post Doctoral Fellow)

Jorg Hohfeld (as Graduate Student - Ph.D.)

Hanns Hatt (as Graduate Student - Masters)
Research:
Molecular cell biology of protein self-assembly and aggregation
Honors:
2009 Margaret and Herman Sokol Postdoctoral Award

2006-2007 Fellowship of the German Research Foundation (DFG)

Communities:

Simon Alberti's Genealogy

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Simon Alberti's Publications (13)

Opposing effects of glutamine and asparagine govern prion formation by intrinsically disordered proteins.
Halfmann R, Alberti S, Krishnan R, Lyle N, O'Donnell CW, King OD, Berger B, Pappu RV, Lindquist S

Molecular cell. 2011 Jul 8;43(1):72-84
Prions, protein homeostasis, and phenotypic diversity.
Halfmann R, Alberti S, Lindquist S

Trends in cell biology. 2010 Mar;20(3):125-33
Biochemical, cell biological, and genetic assays to analyze amyloid and prion aggregation in yeast.
Alberti S, Halfmann R, Lindquist S

Methods in enzymology. 2010;470:709-34
A systematic survey identifies prions and illuminates sequence features of prionogenic proteins.
Alberti S, Halfmann R, King O, Kapila A, Lindquist S

Cell. 2009 Apr 3;137(1):146-58
A suite of Gateway cloning vectors for high-throughput genetic analysis in Saccharomyces cerevisiae.
Alberti S, Gitler AD, Lindquist S

Yeast (Chichester, England). 2007 Oct;24(10):913-9
Identification of VCP/p97, carboxyl terminus of Hsp70-interacting protein (CHIP), and amphiphysin II interaction partners using membrane-based human proteome arrays.
Grelle G, Kostka S, Otto A, Kersten B, Genser KF, Müller EC, Wälter S, Böddrich A, Stelzl U, Hänig C, Volkmer-Engert R, Landgraf C, Alberti S, Höhfeld J, Strödicke M, Wanker EE

Molecular & cellular proteomics : MCP. 2006 Feb;5(2):234-44
BAG-2 acts as an inhibitor of the chaperone-associated ubiquitin ligase CHIP.
Arndt V, Daniel C, Nastainczyk W, Alberti S, Höhfeld J

Molecular biology of the cell. 2005 Dec;16(12):5891-900
Cooperation of molecular chaperones with the ubiquitin/proteasome system.
Esser C, Alberti S, Höhfeld J

Biochimica et biophysica acta. 2004 Nov 29;1695(1-3):171-88
The cochaperone HspBP1 inhibits the CHIP ubiquitin ligase and stimulates the maturation of the cystic fibrosis transmembrane conductance regulator.
Alberti S, Böhse K, Arndt V, Schmitz A, Höhfeld J

Molecular biology of the cell. 2004 Sep;15(9):4003-10
BAG-1--a nucleotide exchange factor of Hsc70 with multiple cellular functions.
Alberti S, Esser C, Höhfeld J

Cell stress & chaperones. 2003;8(3):225-31
Molecular chaperones in the regulation of signal transduction.
Alberti S, Höhfeld J

Annals of the New York Academy of Sciences. 2002 Nov;973:3-4
Ubiquitylation of BAG-1 suggests a novel regulatory mechanism during the sorting of chaperone substrates to the proteasome.
Alberti S, Demand J, Esser C, Emmerich N, Schild H, Hohfeld J

The Journal of biological chemistry. 2002 Nov 29;277(48):45920-7
Cooperation of a ubiquitin domain protein and an E3 ubiquitin ligase during chaperone/proteasome coupling.
Demand J, Alberti S, Patterson C, Höhfeld J

Current biology : CB. 2001 Oct 16;11(20):1569-77

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Simon M Alberti, Ph.D.

Group Leader

Molecular cell biology of protein self-assembly and aggregation

Simon Alberti's Genealogy

Simon Alberti's Publications (13)