Epernicus: Spiro Getsios, Ph.D.

Spiro Getsios, Ph.D.

Position:
Assistant Professor

Dermatology

Northwestern University Feinberg School of Medicine (Chicago, IL)
Degrees:

Ph.D., Reproductive and Developmental Biology, University of British Columbia (Vancouver, Canada)
Past Advisors:

Kathleen J. Green (as Post Doctoral Fellow)

Colin D. MacCalman (as Graduate Student - Ph.D.)
Research:
Cell-cell adhesion and communication in development and disease.

Communities:

Spiro Getsios's Genealogy

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Spiro Getsios's Publications (24)

Enhancement of UVB-induced apoptosis by apigenin in human keratinocytes and organotypic keratinocyte cultures.
Abu-Yousif AO, Smith KA, Getsios S, Green KJ, Van Dross RT, Pelling JC

Cancer research. 2008 Apr 15;68(8):3057-65
Plakoglobin deficiency protects keratinocytes from apoptosis.
Dusek RL, Godsel LM, Chen F, Strohecker AM, Getsios S, Harmon R, Müller EJ, Caldelari R, Cryns VL, Green KJ

The Journal of investigative dermatology. 2007 Apr;127(4):792-801
The differentiation-dependent desmosomal cadherin desmoglein 1 is a novel caspase-3 target that regulates apoptosis in keratinocytes.
Dusek RL, Getsios S, Chen F, Park JK, Amargo EV, Cryns VL, Green KJ

The Journal of biological chemistry. 2006 Feb 10;281(6):3614-24
Mechanisms of plakoglobin-dependent adhesion: desmosome-specific functions in assembly and regulation by epidermal growth factor receptor.
Yin T, Getsios S, Caldelari R, Godsel LM, Kowalczyk AP, Müller EJ, Green KJ

The Journal of biological chemistry. 2005 Dec 2;280(48):40355-63
Plakoglobin suppresses keratinocyte motility through both cell-cell adhesion-dependent and -independent mechanisms.
Yin T, Getsios S, Caldelari R, Kowalczyk AP, Müller EJ, Jones JC, Green KJ

Proceedings of the National Academy of Sciences of the United States of America. 2005 Apr 12;102(15):5420-5
Coordinated expression of desmoglein 1 and desmocollin 1 regulates intercellular adhesion.
Getsios S, Amargo EV, Dusek RL, Ishii K, Sheu L, Godsel LM, Green KJ

Differentiation; research in biological diversity. 2004 Oct;72(8):419-33
Epidermal growth factor receptor inhibition promotes desmosome assembly and strengthens intercellular adhesion in squamous cell carcinoma cells.
Lorch JH, Klessner J, Park JK, Getsios S, Wu YL, Stack MS, Green KJ

The Journal of biological chemistry. 2004 Aug 27;279(35):37191-200
Working out the strength and flexibility of desmosomes.
Getsios S, Huen AC, Green KJ

Nature reviews. Molecular cell biology. 2004 Apr;5(4):271-81
Cadherin switching in ovarian cancer progression.
Patel IS, Madan P, Getsios S, Bertrand MA, MacCalman CD

International journal of cancer. Journal international du cancer. 2003 Aug 20;106(2):172-7
Cadherin-11 modulates the terminal differentiation and fusion of human trophoblastic cells in vitro.
Getsios S, MacCalman CD

Developmental biology. 2003 May 1;257(1):41-54
Syncytiotrophoblast is a barrier to maternal-fetal transmission of herpes simplex virus.
Koi H, Zhang J, Makrigiannakis A, Getsios S, MacCalman CD, Strauss JF, Parry S

Biology of reproduction. 2002 Nov;67(5):1572-9
The barrier function of skin: how to keep a tight lid on water loss.
Tsuruta D, Green KJ, Getsios S, Jones JC

Trends in cell biology. 2002 Aug;12(8):355-7
alpha-, beta-, gamma-catenin, and p120(CTN) expression during the terminal differentiation and fusion of human mononucleate cytotrophoblasts in vitro and in vivo.
Getsios S, Chen GT, MacCalman CD

Molecular reproduction and development. 2001 Jun;59(2):168-77
N-cadherin is regulated by gonadal steroids in adult sexually dimorphic spinal motoneurons.
Monks DA, Getsios S, MacCalman CD, Watson NV

Journal of neurobiology. 2001 Jun 15;47(4):255-64
Differential expression of the coxsackievirus and adenovirus receptor regulates adenovirus infection of the placenta.
Koi H, Zhang J, Makrigiannakis A, Getsios S, MacCalman CD, Kopf GS, Strauss JF, Parry S

Biology of reproduction. 2001 Mar;64(3):1001-9
N-cadherin is regulated by gonadal steroids in the adult hippocampus.
Monks DA, Getsios S, MacCalman CD, Watson NV

Proceedings of the National Academy of Sciences of the United States of America. 2001 Jan 30;98(3):1312-6
Antisteroidal compounds and steroid withdrawal down-regulate cadherin-11 mRNA and protein expression levels in human endometrial stromal cells undergoing decidualisation in vitro.
Chen GT, Getsios S, MacCalman CD

Molecular reproduction and development. 1999 Aug;53(4):384-93
Cadherin-11 is a hormonally regulated cellular marker of decidualization in human endometrial stromal cells.
Chen GT, Getsios S, MacCalman CD

Molecular reproduction and development. 1999 Feb;52(2):158-65
Progesterone regulates beta-catenin mRNA levels in human endometrial stromal cells in vitro.
Chen GT, Getsios S, MacCalman CD

Endocrine. 1998 Dec;9(3):263-7
Regulated expression of cadherin-11 in human extravillous cytotrophoblasts undergoing aggregation and fusion in response to transforming growth factor beta 1.
Getsios S, Chen GT, Huang DT, MacCalman CD

Journal of reproduction and fertility. 1998 Nov;114(2):357-63
17Beta-estradiol potentiates the stimulatory effects of progesterone on cadherin-11 expression in cultured human endometrial stromal cells.
Chen GT, Getsios S, MacCalman CD

Endocrinology. 1998 Aug;139(8):3512-9
Regulated expression of cadherin-6 and cadherin-11 in the glandular epithelial and stromal cells of the human endometrium.
Getsios S, Chen GT, Stephenson MD, Leclerc P, Blaschuk OW, MacCalman CD

Developmental dynamics : an official publication of the American Association of Anatomists. 1998 Mar;211(3):238-47
Type 2 cadherins in the human endometrium and placenta: their putative roles in human implantation and placentation.
MacCalman CD, Getsios S, Chen GT

American journal of reproductive immunology (New York, N.Y. : 1989). 1998 Feb;39(2):96-107
Estrogens potentiate the stimulatory effects of follicle-stimulating hormone on N-cadherin messenger ribonucleic acid levels in cultured mouse Sertoli cells.
MacCalman CD, Getsios S, Farookhi R, Blaschuk OW

Endocrinology. 1997 Jan;138(1):41-8

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Spiro Getsios, Ph.D.

Assistant Professor

Cell-cell adhesion and communication in development and disease.

Spiro Getsios's Genealogy

Spiro Getsios's Publications (24)