Epernicus: Suresh Gopalan, Ph.D.

Suresh Gopalan, Ph.D.

Position:
Founder and President

ReSurfX, LLC
Degrees:

Ph.D., Biotechnology, Anna University (Chennai, India)

B.Eng., Mechanical, Birla Institute of Technology and Science- Pilani (Pilani, India)

M.Sc., Bioscience, Birla Institute of Technology and Science- Pilani (Pilani, India)
Past Advisors:

Fred M Ausubel (as Senior Scientist)
Research:
Host-microbe intearctions, high-throughput multiplexed analyses of signaling
Other Experience:
2006-2010 Assistant in Molecular Biology, Massachusetts General Hospital & Harvard Medical School - Molecular Biology, Center for Computational and Integrative Biology, Genetics

Communities:

Suresh Gopalan's Genealogy

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Suresh Gopalan's Publications (15)

A High Throughput Amenable Arabidopsis-P. aeruginosa System Reveals a Rewired Regulatory Module and the Utility to Identify Potent Anti-Infectives.
Gopalan S, Ausubel FM

PloS one. 2011;6(1):e16381
A metasystem of framework model organisms to study emergence of new host-microbe adaptations.
Gopalan S, Ausubel FM

PloS one. 2008;3(12):e3891
Reversal of an immunity associated plant cell death program by the growth regulator auxin.
Gopalan S

BMC research notes. 2008;1:126
A multidirectional non-cell autonomous control and a genetic interaction restricting tobacco etch virus susceptibility in Arabidopsis.
Gopalan S

PLoS ONE. 2007;2(10):e985
Reversal of an immunity associated plant cell death program by the growth regulator auxin.
Suresh Gopalan

Nature Precedings. 2007
RAR1, a central player in plant immunity, is targeted by Pseudomonas syringae effector AvrB.
Shang Y, Li X, Cui H, He P, Thilmony R, Chintamanani S, Zwiesler-Vollick J, Gopalan S, Tang X, Zhou JM

Proceedings of the National Academy of Sciences of the United States of America. 2006 Dec 12;103(50):19200-5
Local and distant burn injury alter immuno-inflammatory gene expression in skeletal muscle.
Padfield KE, Zhang Q, Gopalan S, Tzika AA, Mindrinos MN, Tompkins RG, Rahme LG

The Journal of trauma. 2006 Aug;61(2):280-92
Proton NMR spectroscopy shows lipids accumulate in skeletal muscle in response to burn trauma-induced apoptosis.
Astrakas LG, Goljer I, Yasuhara S, Padfield KE, Zhang Q, Gopalan S, Mindrinos MN, Dai G, Yu YM, Martyn JA, Tompkins RG, Rahme LG, Tzika AA

The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2005 Sep;19(11):1431-40
Burn injury causes mitochondrial dysfunction in skeletal muscle.
Padfield KE, Astrakas LG, Zhang Q, Gopalan S, Dai G, Mindrinos MN, Tompkins RG, Rahme LG, Tzika AA

Proceedings of the National Academy of Sciences of the United States of America. 2005 Apr 12;102(15):5368-73
The contribution of MvfR to Pseudomonas aeruginosa pathogenesis and quorum sensing circuitry regulation: multiple quorum sensing-regulated genes are modulated without affecting lasRI, rhlRI or the production of N-acyl-L-homoserine lactones.
Déziel E, Gopalan S, Tampakaki AP, Lépine F, Padfield KE, Saucier M, Xiao G, Rahme LG

Molecular microbiology. 2005 Feb;55(4):998-1014
ResurfP: a response surface aided parametric test for identifying differentials in GeneChip based oligonucleotide array experiments.
Suresh Gopalan

Genome Biology. 2004;5(11):P14
Metabolic response of Bacillus sphaericus 1593M for dual-substrate limitation in continuous and total-cell-retention cultures.
Meenakshisundaram S, Suresh Gopalan, Fernando RK, K Jenny, Sachidanandham R, K Jayaraman

Appl. Microbiol. Biotechnol.. 1997;47:554-559
hrp gene-dependent induction of hin1: a plant gene activated rapidly by both harpins and the avrPto gene-mediated signal.
Gopalan S, Wei W, He SY

The Plant journal : for cell and molecular biology. 1996 Oct;10(4):591-600
Expression of the Pseudomonas syringae avirulence protein AvrB in plant cells alleviates its dependence on the hypersensitive response and pathogenicity (Hrp) secretion system in eliciting genotype-specific hypersensitive cell death.
Gopalan S, Bauer DW, Alfano JR, Loniello AO, He SY, Collmer A

The Plant cell. 1996 Jul;8(7):1095-105
Comments on the Lawrence equation for low aspect ratio wings
KB Rajendra, Suresh Gopalan

J. Aircraft. 1989;26:883-885

Suresh Gopalan's Posters and Presentations (8)

A High-Throughput Amenable Metasystem to Study Emergence of Host-Microbe Maladaptations (presentation)
Suresh Gopalan

Broad Institute of Harvard and MIT, Infectious Diseases Initiative; 09/2010
Metasystem for the study of Host-Microbe Adaptations (presentation)
Suresh Gopalan

Sigma Xi Lecture Series, U.S. Army Natick Soldier Research, Development and Engineering Center, Natick, MA; 05/2010
Genetic Analysis of Plant Susceptibility to Tobacco Etch Virus. (presentation)
Suresh Gopalan

New England Arabidopsis Meeting,, The Whitehead Institute, Boston, MA; 11/2001
Identification of putative signaling components in Pseudomonas syringae AvrB-mediated plant disease resistance (presentation)
Suresh Gopalan, Laura Muncie, Sheng Yang He

9th International Conference on Arabidopsis Research, Wisconsin, Madison; 06/1998
Reversal of the plant hypersensitive response by the growth regulator auxin. (presentation)
Suresh Gopalan

The Plant Workshop: Leaves, La-Colle-sur-Soup, France.; 05/1997
Genes galore: how do we get to their functions? (presentation)
Suresh Gopalan

DOE Plant Research Laboratory, Michigan State University, Lansing, Michigan; 11/1996
Pseudomonas syringae pv. glycinea AvrB elicits a genotype specific hypersensitive necrosis in transgenic Arabidopsis thaliana plants: dependence on RPM1 and a possible second target gene. (presentation)
Suresh Gopalan, Sheng Yang He

7th International Conference on Arabidopsis Research, Norwich, UK; 06/1996
Development of a defined medium by chemostat pulse and shift technique for the cultivation of the biopesticide B. sphaericus 1593M. (presentation)
Suresh Gopalan

Swiss Federal Institute of Technology (ETH), Honngerberg, Zurich, Switzerland.; 12/1991

One Figure

ReSurfX: A concept and an algorithm for high confidence utilization of datasets and strategic design of technologies

Websites

ReSurfX

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