Epernicus: Sarath Moses

Sarath Moses

Position:
Senior Scientist

Merck Research Laboratories

Merck & Co., Inc. (Whitehouse Station, NJ)
Degrees:
Past Advisors:

Dieter Soll (as Post Doctoral Fellow)

Isak S Pretorius (as Graduate Student - Ph.D.)
Research:
Cell Culture Process Development and Characterisation.

Communities:

Sarath Moses's Genealogy

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Sarath Moses's Publications (17)

Branchiostoma floridae has separate healing and sealing enzymes for 5'-phosphate RNA ligation.
Englert M, Sheppard K, Gundllapalli S, Beier H, Söll D

Proceedings of the National Academy of Sciences of the United States of America. 2010 Sep 28;107(39):16834-9
A bacterial ortholog of class II lysyl-tRNA synthetase activates lysine.
Ambrogelly A, O'Donoghue P, Söll D, Moses S

FEBS letters. 2010 Jul 16;584(14):3055-60
Distinct genetic code expansion strategies for selenocysteine and pyrrolysine are reflected in different aminoacyl-tRNA formation systems.
Yuan J, O'Donoghue P, Ambrogelly A, Gundllapalli S, Lynn Sherrer R, Palioura S, Simonović M, Söll D

FEBS letters. 2010 Jan 21;584(2):342-9
Translation termination in pyrrolysine-utilizing archaea.
Alkalaeva E, Eliseev B, Ambrogelly A, Vlasov P, Kondrashov FA, Gundllapalli S, Frolova L, Söll D, Kisselev L

FEBS letters. 2009 Nov 3;583(21):3455-60
Pyrrolysyl-tRNA synthetase-tRNA(Pyl) structure reveals the molecular basis of orthogonality.
Nozawa K, O'Donoghue P, Gundllapalli S, Araiso Y, Ishitani R, Umehara T, Söll D, Nureki O

Nature. 2009 Feb 26;457(7233):1163-7
Misacylation of pyrrolysine tRNA in vitro and in vivo.
Gundllapalli S, Ambrogelly A, Umehara T, Li D, Polycarpo C, Söll D

FEBS letters. 2008 Oct 15;582(23-24):3353-8
The Thr505 and Ser557 residues of the AGT1-encoded alpha-glucoside transporter are critical for maltotriose transport in Saccharomyces cerevisiae.
Smit A, Moses SG, Pretorius IS, Cordero Otero RR

Journal of applied microbiology. 2008 Apr;104(4):1103-11
The effect of flocculation on the efficiency of raw-starch fermentation by Saccharomyces cerevisiae producing the Lipomyces kononenkoae LKA1-encoded α-amylase
Nivetha Ramachandran, Lydia Joubert, Sarath B Gundllapalli, Ricardo R Cordero Otero, Isak S Pretorius

Annals of Microbiology. 2008;58(1)
Adding pyrrolysine to the Escherichia coli genetic code.
Namy O, Zhou Y, Gundllapalli S, Polycarpo CR, Denise A, Rousset JP, Söll D, Ambrogelly A

FEBS letters. 2007 Nov 13;581(27):5282-8
Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation.
Kavran JM, Gundllapalli S, O'Donoghue P, Englert M, Söll D, Steitz TA

Proceedings of the National Academy of Sciences of the United States of America. 2007 Jul 3;104(27):11268-73
The amino-terminal domain of pyrrolysyl-tRNA synthetase is dispensable in vitro but required for in vivo activity.
Herring S, Ambrogelly A, Gundllapalli S, O'Donoghue P, Polycarpo CR, Söll D

FEBS letters. 2007 Jul 10;581(17):3197-203
Effect of the cellulose-binding domain on the catalytic activity of a beta-glucosidase from Saccharomycopsis fibuligera.
Gundllapalli SB, Pretorius IS, Cordero Otero RR

Journal of industrial microbiology & biotechnology. 2007 Jun;34(6):413-21
Pyrrolysine is not hardwired for cotranslational insertion at UAG codons.
Ambrogelly A, Gundllapalli S, Herring S, Polycarpo C, Frauer C, Söll D

Proceedings of the National Academy of Sciences of the United States of America. 2007 Feb 27;104(9):3141-6
Characterization of an exocellular β-glucosidase from Debaryomyces pseudopolymorphus
Mara Aravalo Villena, Juan F Ubeda Iranzo, Sarath B Gundllapalli, Ricardo R Cordero Otero, Ana I Briones

Enzyme and Microbial Technology. 2006;39(2):229-235
Development of a screening method for the identification of a novel Saccharomyces cerevisiae mutant over-expressing Trichoderma reesei cellobiohydrolase II.
Sarath b Gundllapalli, Ricardo R Cordero Otero, Isak S Pretorius

Annals of Microbiology. 2006;56(2):95-102
Domain engineering of Saccharomyces cerevisiae exoglucanases.
Moses SB, Otero RR, Pretorius IS

Biotechnology letters. 2005 Mar;27(5):355-62
Different genetic backgrounds influence the secretory expression of the LKA1-encoded Lipomyces kononenkoae -amylase in industrial strains of Saccharomyces cerevisiae
Sarath B Gundllapalli, R.R Cordero Otero, D.C La Grange, P Van Rensburg, I.S Pretorius

Biotechnology Letters. 2002;65:651-656

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Sarath Moses

Senior Scientist

Cell Culture Process Development and Characterisation.

Sarath Moses's Genealogy

Sarath Moses's Publications (17)