Epernicus: Suzanne Gaudet, Ph.D.

Suzanne Gaudet, Ph.D.

Position:
Assistant Professor

Cancer Biology (DFCI)

Genetics (HMS)

Dana-Farber Cancert Institute/Harvard Medical School
Degrees:

Ph.D., Biochemistry, Harvard University (Cambridge, MA)

B.Sc., Biology, University of Montreal (Montreal, Canada)
Past Advisors:

Peter Sorger (as Post Doctoral Fellow)

Daniel Branton (as Graduate Student - Ph.D.)

Rashmi Kothary (as Undergraduate Student)
Research:
Systems biology of cytokine-induced cell signaling

I build and analyze extensive quantitative datasets and computational models to identify key regulators of the dynamics of apoptosis in human cells treated with TNF superfamily ligands.

Communities:

Suzanne Gaudet's Genealogy

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Suzanne Gaudet's Publications (15)

The MEK2-binding tumor suppressor hDlg is recruited by E-cadherin to the midbody ring.
Gaudet S, Langlois MJ, Lue RA, Rivard N, Viel A

BMC cell biology. 2011 Dec 20;12(1):55
Lyapunov exponents and phase diagrams reveal multi-factorial control over TRAIL-induced apoptosis.
Aldridge BB, Gaudet S, Lauffenburger DA, Sorger PK

Molecular systems biology. 2011;7:553
Connecting cell fate decision networks in hematopoeisis from the outside in.
Gaudet S

Molecular systems biology. 2010 Oct 5;6:418
Systematic calibration of a cell signaling network model.
Kim KA, Spencer SL, Albeck JG, Burke JM, Sorger PK, Gaudet S, Kim do H

BMC bioinformatics. 2010;11:202
Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis.
Spencer SL, Gaudet S, Albeck JG, Burke JM, Sorger PK

Nature. 2009 May 21;459(7245):428-32
Collecting and organizing systematic sets of protein data.
Albeck JG, MacBeath G, White FM, Sorger PK, Lauffenburger DA, Gaudet S

Nature reviews. Molecular cell biology. 2006 Nov;7(11):803-12
The response of human epithelial cells to TNF involves an inducible autocrine cascade.
Janes KA, Gaudet S, Albeck JG, Nielsen UB, Lauffenburger DA, Sorger PK

Cell. 2006 Mar 24;124(6):1225-39
A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis.
Janes KA, Albeck JG, Gaudet S, Sorger PK, Lauffenburger DA, Yaffe MB

Science (New York, N.Y.). 2005 Dec 9;310(5754):1646-53
A compendium of signals and responses triggered by prodeath and prosurvival cytokines.
Gaudet S, Janes KA, Albeck JG, Pace EA, Lauffenburger DA, Sorger PK

Molecular & cellular proteomics : MCP. 2005 Oct;4(10):1569-90
Cell stimulus and lysis in a microfluidic device with segmented gas-liquid flow.
El-Ali J, Gaudet S, Günther A, Sorger PK, Jensen KF

Analytical chemistry. 2005 Jun 1;77(11):3629-36
A microfabricated device for subcellular organelle sorting.
Lu H, Gaudet S, Schmidt MA, Jensen KF

Analytical chemistry. 2004 Oct 1;76(19):5705-12
Cue-signal-response analysis of TNF-induced apoptosis by partial least squares regression of dynamic multivariate data.
Janes KA, Kelly JR, Gaudet S, Albeck JG, Sorger PK, Lauffenburger DA

Journal of computational biology : a journal of computational molecular cell biology. 2004;11(4):544-61
Electronic detection of DNA by its intrinsic molecular charge.
Fritz J, Cooper EB, Gaudet S, Sorger PK, Manalis SR

Proceedings of the National Academy of Sciences of the United States of America. 2002 Oct 29;99(22):14142-6
The distribution and function of alternatively spliced insertions in hDlg.
McLaughlin M, Hale R, Ellston D, Gaudet S, Lue RA, Viel A

The Journal of biological chemistry. 2002 Feb 22;277(8):6406-12
Characterization of PDZ-binding kinase, a mitotic kinase.
Gaudet S, Branton D, Lue RA

Proceedings of the National Academy of Sciences of the United States of America. 2000 May 9;97(10):5167-72

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Suzanne Gaudet, Ph.D.

Assistant Professor

Systems biology of cytokine-induced cell signaling

Suzanne Gaudet's Genealogy

Suzanne Gaudet's Publications (15)