Epernicus: Shelly E Sakiyama-Elbert, Ph.D.

Shelly E Sakiyama-Elbert, Ph.D.

Position:
Associate Professor

Biomedical Engineering

Washington University in St. Louis (Saint Louis, MO)
Degrees:

Ph.D., Chemical Engineering, California Institute of Technology (Pasadena, CA)

M.S., Chemical Engineering, California Institute of Technology (Pasadena, CA)

S.B., Chemical Engineering, Massachusetts Institute of Technology (Cambridge, MA)
Past Advisors:

Jeffrey A. Hubbell (as Graduate Student - Ph.D.)
Research:
My lab develops biomaterials for drug delivery and cell transplantation for the treatment of nerve injury.

Communities:

Shelly Sakiyama-Elbert's Genealogy

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Shelly Sakiyama-Elbert's Publications (36)

bFGF and PDGF-BB for tendon repair: controlled release and biologic activity by tendon fibroblasts in vitro.
Thomopoulos S, Das R, Sakiyama-Elbert S, Silva MJ, Charlton N, Gelberman RH

Annals of biomedical engineering. 2010 Feb;38(2):225-34
Fibrin-based tissue engineering scaffolds enhance neural fiber sprouting and delay the accumulation of reactive astrocytes at the lesion in a subacute model of spinal cord injury.
Johnson PJ, Parker SR, Sakiyama-Elbert SE

Journal of biomedical materials research. Part A. 2010 Jan;92(1):152-63
Controlled release of neurotrophin-3 from fibrin-based tissue engineering scaffolds enhances neural fiber sprouting following subacute spinal cord injury.
Johnson PJ, Parker SR, Sakiyama-Elbert SE

Biotechnology and bioengineering. 2009 Dec 15;104(6):1207-14
Controlled release of neurotrophin-3 and platelet derived growth factor from fibrin scaffolds containing neural progenitor cells enhances survival and differentiation into neurons in a subacute model of SCI.
Johnson PJ, Tatara A, Shiu A, Sakiyama-Elbert SE

Cell transplantation. 2009 Oct 9
Anisotropic mechanical properties of magnetically aligned fibrin gels measured by magnetic resonance elastography.
Namani R, Wood MD, Sakiyama-Elbert SE, Bayly PV

Journal of biomechanics. 2009 Sep 18;42(13):2047-53
Conductive Core-Sheath Nanofibers and Their Potential Application in Neural Tissue Engineering.
Xie J, Macewan MR, Willerth SM, Li X, Moran DW, Sakiyama-Elbert SE, Xia Y

Advanced functional materials. 2009 Jul 24;19(14):2312-2318
Controlled release of glial-derived neurotrophic factor from fibrin matrices containing an affinity-based delivery system.
Wood MD, Borschel GH, Sakiyama-Elbert SE

Journal of biomedical materials research. Part A. 2009 Jun 15;89(4):909-18
Affinity-based release of glial-derived neurotrophic factor from fibrin matrices enhances sciatic nerve regeneration.
Wood MD, Moore AM, Hunter DA, Tuffaha S, Borschel GH, Mackinnon SE, Sakiyama-Elbert SE

Acta biomaterialia. 2009 May;5(4):959-68
Neurite outgrowth on nanofiber scaffolds with different orders, structures, and surface properties.
Xie J, MacEwan MR, Li X, Sakiyama-Elbert SE, Xia Y

ACS nano. 2009 May 26;3(5):1151-9
Characterization of a multifunctional PEG-based gene delivery system containing nuclear localization signals and endosomal escape peptides.
Moore NM, Sheppard CL, Sakiyama-Elbert SE

Acta biomaterialia. 2009 Mar;5(3):854-64
Kinetic analysis of neurotrophin-3-mediated differentiation of embryonic stem cells into neurons.
Willerth SM, Sakiyama-Elbert SE

Tissue engineering. Part A. 2009 Feb;15(2):307-18
The differentiation of embryonic stem cells seeded on electrospun nanofibers into neural lineages.
Xie J, Willerth SM, Li X, Macewan MR, Rader A, Sakiyama-Elbert SE, Xia Y

Biomaterials. 2009 Jan;30(3):354-62
Controlled-release kinetics and biologic activity of platelet-derived growth factor-BB for use in flexor tendon repair.
Sakiyama-Elbert SE, Das R, Gelberman RH, Harwood F, Amiel D, Thomopoulos S

The Journal of hand surgery. 2008 Nov;33(9):1548-57
The effect of endosomal escape peptides on in vitro gene delivery of polyethylene glycol-based vehicles.
Moore NM, Sheppard CL, Barbour TR, Sakiyama-Elbert SE

The journal of gene medicine. 2008 Oct;10(10):1134-49
The effect of controlled growth factor delivery on embryonic stem cell differentiation inside fibrin scaffolds.
Willerth SM, Rader A, Sakiyama-Elbert SE

Stem cell research. 2008 Sep;1(3):205-18
Release rate controls biological activity of nerve growth factor released from fibrin matrices containing affinity-based delivery systems.
Wood MD, Sakiyama-Elbert SE

Journal of biomedical materials research. Part A. 2008 Feb;84(2):300-12
Cell therapy for spinal cord regeneration.
Willerth SM, Sakiyama-Elbert SE

Advanced drug delivery reviews. 2008 Jan 14;60(2):263-76
Synthesis and characterization of four-arm poly(ethylene glycol)-based gene delivery vehicles coupled to integrin and DNA-binding peptides.
Moore NM, Barbour TR, Sakiyama-Elbert SE

Molecular pharmaceutics. 2008 Jan-Feb;5(1):140-50
PDGF-BB released in tendon repair using a novel delivery system promotes cell proliferation and collagen remodeling.
Thomopoulos S, Zaegel M, Das R, Harwood FL, Silva MJ, Amiel D, Sakiyama-Elbert S, Gelberman RH

Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2007 Oct;25(10):1358-68
The effects of soluble growth factors on embryonic stem cell differentiation inside of fibrin scaffolds.
Willerth SM, Faxel TE, Gottlieb DI, Sakiyama-Elbert SE

Stem cells (Dayton, Ohio). 2007 Sep;25(9):2235-44
Approaches to neural tissue engineering using scaffolds for drug delivery.
Willerth SM, Sakiyama-Elbert SE

Advanced drug delivery reviews. 2007 May 30;59(4-5):325-38
Development of novel poly(ethylene glycol)-based vehicles for gene delivery.
Schmieder AH, Grabski LE, Moore NM, Dempsey LA, Sakiyama-Elbert SE

Biotechnology and bioengineering. 2007 Apr 1;96(5):967-76
The early effects of sustained platelet-derived growth factor administration on the functional and structural properties of repaired intrasynovial flexor tendons: an in vivo biomechanic study at 3 weeks in canines.
Gelberman RH, Thomopoulos S, Sakiyama-Elbert SE, Das R, Silva MJ

The Journal of hand surgery. 2007 Mar;32(3):373-9
Rationally designed peptides for controlled release of nerve growth factor from fibrin matrices.
Willerth SM, Johnson PJ, Maxwell DJ, Parsons SR, Doukas ME, Sakiyama-Elbert SE

Journal of biomedical materials research. Part A. 2007 Jan;80(1):13-23
Optimization of fibrin scaffolds for differentiation of murine embryonic stem cells into neural lineage cells.
Willerth SM, Arendas KJ, Gottlieb DI, Sakiyama-Elbert SE

Biomaterials. 2006 Dec;27(36):5990-6003

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Websites

Sakiyama-Elbert Lab Page

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