Epernicus: Steve Dorus, Ph.D.

Steve Dorus, Ph.D.

Position:
Lecturer

Biology and Biochemistry

University of Bath (Bath, UK)
Degrees:

Ph.D., Genetics, University of Chicago (Chicago, IL)
Past Advisors:

tim l karr (as Post Doctoral Fellow)

Bruce T. Lahn (as Graduate Student - Ph.D.)
Research:
Evolutionary genetics of reproduction
Honors:
2005-present Research Council of the United Kingdom Fellowship

2006-2008 Ruth L. Kirschstein National Research Service Award, National

2004-2005 William Rainey Harper Fellowship- University of Chicago

Communities:

Steve Dorus's Genealogy

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Steve Dorus's Publications (15)

Rapid Virulence Annotation (RVA): identification of virulence factors using a bacterial genome library and multiple invertebrate hosts.
Waterfield NR, Sanchez-Contreras M, Eleftherianos I, Dowling A, Wilkinson P, Parkhill J, Thomson N, Reynolds SE, Bode HB, Dorus S, Ffrench-Constant RH

Proceedings of the National Academy of Sciences of the United States of America. 2008 Oct 14;105(41):15967-72
Recent origins of sperm genes in Drosophila.
Dorus S, Freeman ZN, Parker ER, Heath BD, Karr TL

Molecular biology and evolution. 2008 Oct;25(10):2157-66
Sperm Genomics and Proteomics (book chapter)
Steve Dorus, Timothy T Karr

Sperm Evolution. 2008
Adaptive evolution of genes underlying schizophrenia.
Crespi B, Summers K, Dorus S

Proceedings. Biological sciences / The Royal Society. 2007 Nov 22;274(1627):2801-10
Genomic and functional evolution of the Drosophila melanogaster sperm proteome.
Dorus S, Busby SA, Gerike U, Shabanowitz J, Hunt DF, Karr TL

Nature genetics. 2006 Dec;38(12):1440-5
Sonic Hedgehog, a key development gene, experienced intensified molecular evolution in primates.
Dorus S, Anderson JR, Vallender EJ, Gilbert SL, Zhang L, Chemnick LG, Ryder OA, Li W, Lahn BT

Human molecular genetics. 2006 Jul 1;15(13):2031-7
A sperm's eye view of evolution
Timothy L Karr, Steve Dorus, Ursula Gerike

INTEGRATIVE AND COMPARATIVE BIOLOGY. 2006;46:E73-E73
Expansion of sperm gene families in D. melanogaster
Steve Dorus

INTEGRATIVE AND COMPARATIVE BIOLOGY. 2006;46:E35-E35
Origin and neofunctionalization of a Drosophila paternal effect gene essential for zygote viability.
Loppin B, Lepetit D, Dorus S, Couble P, Karr TL

Current biology : CB. 2005 Jan 26;15(2):87-93
Accelerated evolution of nervous system genes in the origin of Homo sapiens.
Dorus S, Vallender EJ, Evans PD, Anderson JR, Gilbert SL, Mahowald M, Wyckoff GJ, Malcom CM, Lahn BT

Cell. 2004 Dec 29;119(7):1027-40
Rate of molecular evolution of the seminal protein gene SEMG2 correlates with levels of female promiscuity.
Dorus S, Evans PD, Wyckoff GJ, Choi SS, Lahn BT

Nature genetics. 2004 Dec;36(12):1326-9
Adaptive evolution of ASPM, a major determinant of cerebral cortical size in humans.
Evans PD, Anderson JR, Vallender EJ, Gilbert SL, Malcom CM, Dorus S, Lahn BT

Human molecular genetics. 2004 Mar 1;13(5):489-94
The CDY-related gene family: coordinated evolution in copy number, expression profile and protein sequence.
Dorus S, Gilbert SL, Forster ML, Barndt RJ, Lahn BT

Human molecular genetics. 2003 Jul 15;12(14):1643-50
Substrate-binding clusters of the K+-transporting Kdp ATPase of Escherichia coli investigated by amber suppression scanning mutagenesis.
Dorus S, Mimura H, Epstein W

The Journal of biological chemistry. 2001 Mar 30;276(13):9590-8
Modulation of KdpD phosphatase implicated in the physiological expression of the kdp ATPase of Escherichia coli.
Brandon L, Dorus S, Epstein W, Altendorf K, Jung K

Molecular microbiology. 2000 Dec;38(5):1086-92

Steve Dorus's Posters and Presentations (7)

Proteomic and genomic approaches to characterizing sperm composition (presentation)
Steve Dorus

University of Exeter; 05/2008
The human brain: evolutionary genetics, adaptation and schizophrenia (presentation)
Steve Dorus

Bath Royal Literary and Scientific Society; 10/2007
Proteomic and genomic approaches to characterizing sperm composition (presentation)
Steve Dorus

Biology of Spermatazoa; 06/2007
Comparative whole-cell proteomics: the evolution of a gamete (presentation)
Steve Dorus

Society of Integrative and Comparative Biology, Annual Conference; 01/2007
Rapid expansion and neofunctionalization of sperm genes (presentation)
Steve Dorus

Society of Molecular Biology and; 06/2006
The Drosophila melanogaster sperm proteome: A study of function, genome organization and evolution (presentation)
Steve Dorus

Trinity College- Smurfit Institute of Genetics; 06/2006
Evolutionary genetics of the Drosophila melanogaster sperm proteome (poster)
Steve Dorus

Biology of Spermatazoa, University of Sheffield; 06/2005

One Figure

Genomic distribution of D. melanogaster sperm genes

Websites

Research Profile- University of Bath

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