Rachel V Woodruff

Rachel V Woodruff, Ph.D.

  • Position:
    Post Doctoral Associate

    Biology

    Massachusetts Institute of Technology (Cambridge, MA)

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  • Advisor:

    Graham Walker

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  • Degrees:
     
    Ph.D., Biology, Massachusetts Institute of Technology (Cambridge, MA)
     
    B.A., Molecular Biophysics and Biochemistry, Yale University (New Haven, CT)
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  • Past Advisors:
     
    Guido Guidotti (as Research Associate)
     
    Thomas A Steitz (as Undergraduate Student)
     
    Craig M. Crews (as Undergraduate Student)
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  • Research:
    I study the regulation of specialized DNA polymerases, and their roles in the cellular response to DNA damage, in S. cerevisiae.

    My research is focused on DNA damage tolerance, in particular through translesion synthesis (TLS), a process in which specialized DNA polymerases are used to replicate damaged DNA. TLS can be a highly mutagenic or an error-free process, depending on the specific polymerase and lesion. Therefore, it has important implications for both the initiation and treatment of human cancers. However, I do most of my work in the model organism Saccharomyces cerevisiae.

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  • Other Experience:

    2009 Technical Instructor, MIT Department of Biology

Life Sciences
Health Sciences
Communities:

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