Epernicus: Rajaraman Krishnan, Ph.D.

Rajaraman Krishnan, Ph.D.

Position:
Post Doctoral Associate

Lindquist Lab

Whitehead Institute for Biomedical Research (Cambridge, MA)
Advisor:
Susan Lindquist
Degrees:

Ph.D., Biochemistry, Centre for Cellular and Molecular Biology (Hyderabad, India), Jawaharlal Nehru University (Delhi, India)
Past Advisors:

Rao Ch. Mohan (as Graduate Student - Ph.D.)
Research:

Communities:

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Direct and selective elimination of specific prions and amyloids by 4,5-dianilinophthalimide and analogs.
Wang H, Duennwald ML, Roberts BE, Rozeboom LM, Zhang YL, Steele AD, Krishnan R, Su LJ, Griffin D, Mukhopadhyay S, Hennessy EJ, Weigele P, Blanchard BJ, King J, Deniz AA, Buchwald SL, Ingram VM, Lindquist S, Shorter J

Proceedings of the National Academy of Sciences of the United States of America. 2008 May 20;105(20):7159-64
A natively unfolded yeast prion monomer adopts an ensemble of collapsed and rapidly fluctuating structures.
Mukhopadhyay S, Krishnan R, Lemke EA, Lindquist S, Deniz AA

Proceedings of the National Academy of Sciences of the United States of America. 2007 Feb 20;104(8):2649-54
Structural insights into a yeast prion illuminate nucleation and strain diversity.
Krishnan R, Lindquist SL

Nature. 2005 Jun 9;435(7043):765-72
Effects of Q/N-rich, polyQ, and non-polyQ amyloids on the de novo formation of the [PSI+] prion in yeast and aggregation of Sup35 in vitro.
Derkatch IL, Uptain SM, Outeiro TF, Krishnan R, Lindquist SL, Liebman SW

Proceedings of the National Academy of Sciences of the United States of America. 2004 Aug 31;101(35):12934-9

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