Rebecca A Penkala

Rebecca A Penkala, B.Sc.

  • Position:
    Graduate Student - Ph.D.

    Bioengineering

    University of Washington (Seattle, WA)

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  • Advisor:

    Wendy Thomas

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  • Degrees:
     
    B.Sc., Biomedical Engineering, Rutgers University (New Brunswick, NJ)
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  • Past Advisors:
     
    Stephen S Kim (as Graduate Student - Ph.D.)
     
    Moghe, Probas (as Undergraduate Student)
     
    Stanley M Dunn (as Undergraduate Student)
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  • Research:
    I study the biophysics of the bond between platelets, a non-nucleated blood cell, and von Willebrand's Factor, a blood protein, essential in blood clotting.

    Thrombus formation in areas of high shear is mediated by binding between the GPIbα protein expressed on the surface of platelets and von Willebrand Factor (vWF), a protein found in the blood. Mature vWF is composed of a series of subunits designated as follows beginning from the N-terminus: D’-D3-A1-A2-A3-D4-B1-B2-B3-C1-C2-CK. The binding of GPIbα to the A1 domain of vWF is enhanced in the presence of shear stress. The mechanism by which this binding is regulated is poorly understood and is the focus of my research.

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  • Other Experience:

    2003 Laboratory Intern, Lucent Technologies Bell Labs, Murray Hill, NJ

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  • Honors:

    2007-present NSF Graduate Research Fellowship

    2005-2008 ARCS Fellow

    2005 Samuel Walkowitz Award for Excellence in Biomedical Engineerin

    2004-2005 Tau Beta Pi Engineering Honor Society

    2004 IGERT (Integrative Graduate Education and Research Traineeship Program) Summer Undergraduate Research Frontiers Fellow (ISURF)

    2004-2005 Rutgers Undergraduate Research Fellowship

    2004 David and Dorothy Bernstein Scholarship for Research recipient

    2004-2005 Alpha Eta Mu Beta the Biomedical Engineering Honor Society

    2001-2005 Jane Forsyth Garrity Scholarship

    2001-2005 Edward J. Bloustein Distinguished Scholar

    2001-2005 Rutgers University Merit Award

Life Sciences
Communities:

Rebecca Penkala's Genealogy

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Rebecca Penkala's Publications (5)



Rebecca Penkala's Posters and Presentations (2)

  • The Evaluation of a Perfusion Bioreactor for Culture of Intestinal Cells Under Physiologic Conditions. (poster)

    Rebecca A Penkala

    BMES; 09/2007
  • Ligand Functionalized Nanoparticles for Engineering Skin Epidermal Cell Behavior. (poster)

    Rebecca A Penkala

    BMES; 09/2004

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