Epernicus: Qian Yin, Ph.D.

Qian Yin, Ph.D.

Position:
Post Doctoral Fellow

Biochemistry

Weill Cornell Medical College (New York, NY)
Advisor:
Hao Wu
Degrees:

Ph.D., Biochemistry and Structural Biology, Tri-Institutional Program in Chemical Biology (Weill Cornell/Rockefeller/Sloan-Kettering) (New York, NY)

B.S., Chemistry, Tsinghua University (Beijing, China)
Past Advisors:

Hao Wu (as Graduate Student - Ph.D.)
Research:
Structural studies of signaling proteins in innate immunity and inflammatory responses

Communities:

Qian Yin's Genealogy

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Qian Yin's Publications (12)

Multimeric assembly and biochemical characterization of the Trax-translin endonuclease complex.
Tian Y, Simanshu DK, Ascano M, Diaz-Avalos R, Park AY, Juranek SA, Rice WJ, Yin Q, Robinson CV, Tuschl T, Patel DJ

Nature structural & molecular biology. 2011 Jun;18(6):658-64
Mutational analysis of TRAF6 reveals a conserved functional role of the RING dimerization interface and a potentially necessary but insufficient role of RING-dependent TRAF6 polyubiquitination towards NF-κB activation.
Megas C, Hatzivassiliou EG, Yin Q, Marinopoulou E, Hadweh P, Vignali DA, Mosialos G

Cellular signalling. 2011 May;23(5):772-7
Structural studies of NF-κB signaling.
Zheng C, Yin Q, Wu H

Cell research. 2011 Jan;21(1):183-95
Structural studies of NEMO and TRAF6: implications in NF-κB activation.
Wu H, Lo YC, Yin Q

Advances in experimental medicine and biology. 2011;691:89-91
The Fas-FADD death domain complex structure reveals the basis of DISC assembly and disease mutations.
Wang L, Yang JK, Kabaleeswaran V, Rice AJ, Cruz AC, Park AY, Yin Q, Damko E, Jang SB, Raunser S, Robinson CV, Siegel RM, Walz T, Wu H

Nature structural & molecular biology. 2010 Nov;17(11):1324-9
Structural basis for the lack of E2 interaction in the RING domain of TRAF2.
Yin Q, Lamothe B, Darnay BG, Wu H

Biochemistry. 2009 Nov 10;48(44):10558-67
E2 interaction and dimerization in the crystal structure of TRAF6.
Yin Q, Lin SC, Lamothe B, Lu M, Lo YC, Hura G, Zheng L, Rich RL, Campos AD, Myszka DG, Lenardo MJ, Darnay BG, Wu H

Nature structural & molecular biology. 2009 Jun;16(6):658-66
PHAPI/pp32 suppresses tumorigenesis by stimulating apoptosis.
Pan W, da Graca LS, Shao Y, Yin Q, Wu H, Jiang X

The Journal of biological chemistry. 2009 Mar 13;284(11):6946-54
A dimeric Smac/diablo peptide directly relieves caspase-3 inhibition by XIAP. Dynamic and cooperative regulation of XIAP by Smac/Diablo.
Gao Z, Tian Y, Wang J, Yin Q, Wu H, Li YM, Jiang X

The Journal of biological chemistry. 2007 Oct 19;282(42):30718-27
Molecular basis for the unique specificity of TRAF6.
Chung JY, Lu M, Yin Q, Lin SC, Wu H

Advances in experimental medicine and biology. 2007;597:122-30
Structural revelations of TRAF2 function in TNF receptor signaling pathway.
Chung JY, Lu M, Yin Q, Wu H

Advances in experimental medicine and biology. 2007;597:93-113
Caspase-9 holoenzyme is a specific and optimal procaspase-3 processing machine.
Yin Q, Park HH, Chung JY, Lin SC, Lo YC, da Graca LS, Jiang X, Wu H

Molecular cell. 2006 Apr 21;22(2):259-68

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Qian Yin, Ph.D.

Post Doctoral Fellow

Structural studies of signaling proteins in innate immunity and inflammatory responses

Qian Yin's Genealogy

Qian Yin's Publications (12)