
Biology
Molecular Biology and Biotechnology
University of North Carolina at Chapel Hill (Chapel Hill, NC)
We study mechanisms that prevent mitotic crossovers in cycling cells and mechanisms that promote meiotic crossovers, using Drosophila as a model. Much of our mitotic recombination work has focused on the Drosophila BLM helicase and associated proteins, whereas our meiotic work has focused on the putative Holliday junction resolvase containing MEI-9 (XPF/Rad1), ERCC1, and MUS312 (BTBD12/Slx4). Additional studies of meiotic recombination investigate REC (MCM8) and interacting proteins.
2008-2010 Glenn Award for research on biological mechanisms of aging
2000-2004 Ellison Medical Foundation New Scholar Award
1995-1998 Damon Runyon - Walter Winchell Postdoctoral Fellowship

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