Epernicus: Samuel J Lord, Ph.D.

Samuel J Lord, Ph.D.

Position:
Postdoctoral Fellow

QB3

Chemistry

University of California, Berkeley (Berkeley, CA)
Advisor:
Jay T. Groves
Degrees:

Ph.D., Chemistry, Stanford University (Stanford, CA)

B.S., Chemistry, University of North Carolina at Chapel Hill (Chapel Hill, NC)
Past Advisors:

W. E. Moerner (as Graduate Student - Ph.D.)

Sergei S. Sheiko (as Undergraduate Student)

Steven Chu (as Undergraduate Student)

Eric S G Shaqfeh (as Undergraduate Student)
Research:
imaging cell signaling
Honors:
2010-2012 Irving S. Sigal Postdoctoral Fellowship

2008 Bio-X Travel Award Subsidy

2008 Sessler Graduate Student Leadership Award

2004 Hypercube Scholar

2002 National Starch and Chemical Company Award

Communities:

Samuel Lord's Genealogy

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Samuel Lord's Publications (12)

Superresolution Imaging of Targeted Proteins in Fixed and Living Cells Using Photoactivatable Organic Fluorophores.
Lee HL, Lord SJ, Iwanaga S, Zhan K, Xie H, Williams JC, Wang H, Bowman GR, Goley ED, Shapiro L, Twieg RJ, Rao J, Moerner WE

Journal of the American Chemical Society. 2010 Oct 11
Single-molecule spectroscopy and imaging of biomolecules in living cells.
Lord SJ, Lee HL, Moerner WE

Analytical chemistry. 2010 Mar 15;82(6):2192-203
Molecules and methods for super-resolution imaging.
Thompson MA, Biteen JS, Lord SJ, Conley NR, Moerner WE

Methods in enzymology. 2010;475:27-59
Azido Push-Pull Fluorogens Photoactivate to Produce Bright Fluorescent Labels (dagger).
Lord SJ, Lee HL, Samuel R, Weber R, Liu N, Conley NR, Thompson MA, Twieg RJ, Moerner WE

The journal of physical chemistry. B. 2009 Oct 27
Three-dimensional, single-molecule fluorescence imaging beyond the diffraction limit by using a double-helix point spread function.
Pavani SR, Thompson MA, Biteen JS, Lord SJ, Liu N, Twieg RJ, Piestun R, Moerner WE

Proceedings of the National Academy of Sciences of the United States of America. 2009 Mar 3;106(9):2995-9
Bright, Red Single-Molecule Emitters: Synthesis and Properties of Environmentally Sensitive Dicyanomethylenedihydrofuran (DCDHF) Fluorophores with Bisaromatic Conjugation.
Lu Z, Liu N, Lord SJ, Bunge SD, Moerner WE, Twieg RJ

Chemistry of materials : a publication of the American Chemical Society. 2009 Feb 5;21(5):797-810
DCDHF fluorophores for single-molecule imaging in cells.
Lord SJ, Conley NR, Lee HL, Nishimura SY, Pomerantz AK, Willets KA, Lu Z, Wang H, Liu N, Samuel R, Weber R, Semyonov A, He M, Twieg RJ, Moerner WE

Chemphyschem : a European journal of chemical physics and physical chemistry. 2009 Jan 12;10(1):55-65
A photoactivatable push-pull fluorophore for single-molecule imaging in live cells.
Lord SJ, Conley NR, Lee HL, Samuel R, Liu N, Twieg RJ, Moerner WE

Journal of the American Chemical Society. 2008 Jul 23;130(29):9204-5
Photophysical properties of acene DCDHF fluorophores: long-wavelength single-molecule emitters designed for cellular imaging.
Lord SJ, Lu Z, Wang H, Willets KA, Schuck PJ, Lee HL, Nishimura SY, Twieg RJ, Moerner WE

The journal of physical chemistry. A. 2007 Sep 20;111(37):8934-41
Modifications of DCDHF single molecule fluorophores to impart water solubility.
Wang H, Lu Z, Lord SJ, Moerner WE, Twieg RJ

Tetrahedron letters. 2007 May 7;48(19):3471-3474
Long-wavelength analogue of PRODAN: synthesis and properties of Anthradan, a fluorophore with a 2,6-donor-acceptor anthracene structure.
Lu Z, Lord SJ, Wang H, Moerner WE, Twieg RJ

The Journal of organic chemistry. 2006 Dec 22;71(26):9651-7
Diffusion of lipid-like single-molecule fluorophores in the cell membrane.
Nishimura SY, Lord SJ, Klein LO, Willets KA, He M, Lu Z, Twieg RJ, Moerner WE

The journal of physical chemistry. B. 2006 Apr 20;110(15):8151-7

One Figure

Photoactivation of azido DCDHF fluorogens.

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