Epernicus: Jason Yongsheng Chan, M.B.B.S.

Jason Yongsheng Chan, M.B.B.S.

Position:
Resident

Internal Medicine

Singapore Health Services, Singapore
Degrees:

M.B.B.S., National University of Singapore (Kent Ridge, Singapore)
Past Advisors:
Research:
My principle interests circumscribe the topic of genetic instability in cancer cells, as well as on the notion of "uncertainty" in epistemology, life, and other fields.

Communities:

Jason Yongsheng Chan's Genealogy

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Jason Yongsheng Chan's Publications (20)

8q24 and 17q Prostate Cancer Susceptibility Loci in a Multiethnic Asian Cohort
Chan JY, Li HH, Singh O, Mahajan A, Ramasamy S, Subramaniyan K, Kanesvaran R, Sim HG, Chong TW, Teo YY, Chia SE, Tan MH, Chowbay B

Urologic Oncology. (in press)
Functional Hand Proportion is Approximated by the Fibonacci Series
KW Choo, WK Quah, GH Chang, JY Chan

Folia Morphologica. (in press)
The Stomach: Stem Cells of the Gastric Mucosa & Precursor Lesions of Gastric Adenocarcinoma
MM Subramaniam, JY Chan, KG Yeoh, M Salto-Tellez

Gastrointestinal Tumorigenesis: The Relevance of Tumorigenic Mechanisms to Diagnosis and Treatment. (in press)
On genetic information uncertainty and the mutator phenotype in cancer.
Chan JY

Bio Systems. 2012 Apr;108(1-3):28-33
Proteomic Identification of Chaperonin-containing Tail-less Complex Polypeptide-1 Gamma Subunit as a p53-responsive Protein in Colon Cancer Cells.
Lee SC, Chan J

Cancer genomics & proteomics. 2012 Mar;9(2):101-8
Overexpression of neurone glial-related cell adhesion molecule is an independent predictor of poor prognosis in advanced colorectal cancer.
Chan JY, Ong CW, Salto-Tellez M

Cancer science. 2011 Oct;102(10):1855-61
Xenobiotic and folate pathway gene polymorphisms and risk of childhood acute lymphoblastic leukaemia in Javanese children.
Chan JY, Ugrasena DG, Lum DW, Lu Y, Yeoh AE

Hematological oncology. 2011 Sep;29(3):116-23
A clinical overview of centrosome amplification in human cancers.
Chan JY

International journal of biological sciences. 2011;7(8):1122-44
Objective effect manifestation of pectus excavatum on load-stressed pulmonary function testing: a case report.
Chan JY, Huang WL

Journal of medical case reports. 2011;5(1):592
Vestiphobia in a military conscript: a case report
JY Chan

Grand Rounds. 2011;11:41-43
Lack of RUNX3 inactivation in columnar cell lesions of breast.
Subramaniam MM, Chan JY, Omar MF, Ito K, Ito Y, Yeoh KG, Salto-Tellez M, Putti TC

Histopathology. 2010 Oct;57(4):555-63
Genetic susceptibility to childhood acute lymphoblastic leukemia shows protection in Malay boys: results from the Malaysia-Singapore ALL Study Group.
Yeoh AE, Lu Y, Chan JY, Chan YH, Ariffin H, Kham SK, Quah TC

Leukemia research. 2010 Mar;34(3):276-83
Spontaneous and 5-fluorouracil-induced centrosome amplification lowers the threshold to resveratrol-evoked apoptosis in colon cancer cells.
Lee SC, Chan JY, Pervaiz S

Cancer letters. 2010 Feb 1;288(1):36-41
Molecular pathology of RUNX3 in human carcinogenesis.
Subramaniam MM, Chan JY, Yeoh KG, Quek T, Ito K, Salto-Tellez M

Biochimica et biophysica acta. 2009 Dec;1796(2):315-31
Scutellarin sensitizes drug-evoked colon cancer cell apoptosis through enhanced caspase-6 activation.
Chan JY, Tan BK, Lee SC

Anticancer research. 2009 Aug;29(8):3043-7
RUNX3 inactivation in colorectal polyps arising through different pathways of colonic carcinogenesis.
Subramaniam MM, Chan JY, Soong R, Ito K, Yeoh KG, Wong R, Guenther T, Will O, Chen CL, Kumarasinghe MP, Ito Y, Salto-Tellez M

The American journal of gastroenterology. 2009 Feb;104(2):426-36
RUNX3 inactivation by frequent promoter hypermethylation and protein mislocalization constitute an early event in breast cancer progression.
Subramaniam MM, Chan JY, Soong R, Ito K, Ito Y, Yeoh KG, Salto-Tellez M, Putti TC

Breast cancer research and treatment. 2009 Jan;113(1):113-21
The Golden Ratio Optimizes Cardiomelic Form and Function
JY Chan, GH Chang

Iranian Journal of Medical Hypotheses and Ideas. 2009;3:1-5
Resveratrol displays converse dose-related effects on 5-fluorouracil-evoked colon cancer cell apoptosis: the roles of caspase-6 and p53.
Chan JY, Phoo MS, Clement MV, Pervaiz S, Lee SC

Cancer biology & therapy. 2008 Aug;7(8):1305-12
Functional proteomics of resveratrol-induced colon cancer cell apoptosis: caspase-6-mediated cleavage of lamin A is a major signaling loop.
Lee SC, Chan J, Clement MV, Pervaiz S

Proteomics. 2006 Apr;6(8):2386-94

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Jason Yongsheng Chan, M.B.B.S.

Resident

My principle interests circumscribe the topic of genetic instability in cancer cells, as well as on the notion of "uncertainty" in epistemology, life, and other fields.

Jason Yongsheng Chan's Genealogy

Jason Yongsheng Chan's Publications (20)