Director

High-Throughput Bioscience Center

Chemical and Systems Biology

Stanford University School of Medicine (Stanford, CA)

The High-Throughput Bioscience Center's mission is to provide researchers at Stanford with the ability to run high-throughput chemical, siRNA, cDNA, and high-content screens for the purpose of drug and/or target discovery.

Research approaches that were previously done exclusively in industry are now being used in academia to advance basic research. This high-throughput screening (HTS) laboratory allows Stanford researchers and others to discover novel modulators of targets that otherwise would not be practical in industry. The center incorporates instrumentation (purchased with NCRR NIH Instrumentation grant number 1S10RR019513-01), databases, compound libraries, and personnel whose previous sole domains were in industry. Among our instrumentation are a Molecular Devices ImageXpress Micro fluorescence microplate imager, with live cell option, a Caliper Life Sciences SciClone ALH3000 microplate liquid handler and the Molecular Devices Analyst GT and FlexStation II 384 fluorescence, luminescence and absorbance microplate readers. We have over 130,000 small molecules for compound screens, 12,000 cDNAs for genomic screens, and the siARRAY whole human genome siRNA library from ThermoFisher Scientific (formerly Dharmacon) targeting 21,000 genes.

1999-2003 Principal Scientist, Ceretek, LLC.

1995-1999 Scientist, FibroGen, Inc.

1991-1992 University Fellowship, University of California at Berkeley

1986-1987 National Hispanic Scholar, MIT