Carolyn L Cannon

Carolyn L Cannon, M.D., Ph.D.

  • Position:
    Associate Professor of Pediatrics

    Division of Respiratory Medicine

    University of Texas Southwestern Medical Center (Dallas, TX)

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  • Degrees:
     
    M.D., University of Texas Health Science Center at Houston (Houston, TX)
     
    Ph.D., Physiology and Cell Biology, University of Texas School of Biological Sciences (Austin, TX)
     
    M.S., Electrical Engineering, Worcester Polytechnic Institute (Worcester, MA)
     
    B.Sc., Bioengineering, Texas A&M University (College Station, TX)
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  • Clinical Training:
     
    Fellowship, Pediatric Pulmonology, Children's Hospital Boston
     
    Residency, Pediatrics, Children's Hospital Boston
     
    Internship, Pediatrics, Children's Hospital Boston
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  • Past Advisors:
     
    Gerald B Pier (as Clinical Fellow)
     
    William P Dubinsky (as Graduate Student - Ph.D.)
     
    Walter S Kuklinski (as Graduate Student - Masters)
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  • Research:
    Basic Research. Project Title: Silver carbene complexes as treatment of CF lung disease.

    The long-term goal of these studies is to explore the utility of silver carbene complexes as antimicrobial agents in the treatment of chronic infections of the cystic fibrosis (CF) lung. Silver N-heterocyclic carbene complexes have antimicrobial activity against all bacterial species tested to date, including the CF lung pathogens Pseudomonas aeruginosa and Burkholderia cepacia complex (Bcc) organisms. Silver carbene complexes are water soluble, and hence amenable to nebulization for drug delivery. Silver complexes are currently used as antimicrobials to treat Staphylococcus aureus and P. aeruginosa infections in burn patients and have a long history of safe use for these topical applications. The use of silver compounds to treat pulmonary infections, however, has not been explored, a deficit we will address in this project.

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Life Sciences
Health Sciences
Physical Sciences
Communities:

Carolyn Cannon's Genealogy

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Carolyn Cannon's Publications (27)



Carolyn Cannon's Posters and Presentations (3)

  • Comparison of Two Nebulized Silver Carbene Complexes; SCC1 and SCC5, as Treatment for a Murine Model of Pseudomonas aeruginosa Pneumonia (poster)

    Jane B. Taylor, Khadijah M. Hindi, Daniel S. Han, Aysegul Kascatan-Nebioglu, Wiley J. Youngs, Carolyn L. Cannon

    American Thoracic Society, International Conference 2009, San Diego CA; 05/2009
  • Nanoparticles Loaded with Broad-Spectrum Silver-Based Antimicrobials for Depot Delivery of Therapy for Pulmonary Infections (poster)

    Cannon L. Cannon, Dan S. Han, Jane B. Taylor, Andrew J. Ditto, Khadijah M. Hindi, Matthew J. Panzner, Sean P. Gunsten, Michael J. Walter, Yang H. Yun, Wiley J. Youngs

    American Thoracic Society, International Conference 2009, San Diego CA; 05/2009
  • Superiority of Nebulized Methylated Caffeine Silver Acetate, SCC1, over Tobramycin for Treatment of Multi-Drug Resistant Pseudomonas aeruginosa in a Mouse Model of Pneumonia (poster)

    Daniel S. Han, Peter Shin, Steve Chung, Chan Lee, Brian D. Wright, Wiley J. Youngs, Carolyn L. Cannon

    American Thoracic Society, International Conference 2009, San Diego CA; 05/2009
    Attachment: 2009_ATS_Han.pdf

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