Nader H Moniri

Nader H Moniri, Ph.D.

  • Position:
    Assistant Professor

    Pharmaceutical Sciences

    Mercer University College of Pharmacy and Health Sciences

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  • Degrees:
     
    Ph.D., Pharmaceutical Sciences, University of North Carolina at Chapel Hill (Chapel Hill, NC)
     
    B.S., Biological Sciences, Georgia State University (Atlanta, GA)
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  • Past Advisors:
     
    Yehia Daaka (as Post Doctoral Fellow)
     
    Raymond G. Booth (as Graduate Student - Ph.D.)
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  • Research:
    Dr. Moniri's training has focused on molecular pharmacology and signal transduction of G protein-coupled receptors (GPCR) as well as the design and development of novel agents which modulate GPCR function.

    Current research interests include signal transduction, alternative signaling, and design of functionally selective modulators of the prototypical GPCR, the beta-2-adrenergic receptor. Specifically, this work seeks to characterize mechanisms of beta-2-receptor mediated generation of intracellular reactive oxygen species, formation of which we have recently shown to be indispensable for receptor function.

    The Moniri lab is also interested in characterization of neuro-endocrine GPCRs which are involved in glucagon/insulin homeostasis, food intake, and satiety, as well as development of novel anti-diabetic agents which target these GPCRs. One such project focuses on intracellular signaling of the recently discovered long chain free fatty acid receptor GPR120.

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  • Other Experience:

    2005-2006 Senior Scientist, Neurogen Corporation

    2004-2005 Post-Doctoral Fellow, Duke University Medical Center

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  • Honors:

    2010 Teacher of the Year Award, Rho Chi Pharmacy Honor Society, Mercer University Chapter

    2010 Nominatee, Mercer University Excellence in Teaching Award

    2010 Class of 2010, Elected Graduation Hooder, Mercer University College of Pharmacy and Health Sciences

    2009 Class of 2009, Elected Graduation Hooder, Mercer University College of Pharmacy and Health Sciences

    2008 Teacher of the Year Award, Rho Chi Pharmacy Honor Society, Mercer University Chapter

    2008 Class of 2008, Elected Graduation Marshall, Mercer University College of Pharmacy and Health Sciences

    2007 New Professor Recognition Award, Rho Chi Pharmacy Honor Society, Mercer University

    2006 Inductee, Cambridge’s Who’s Who in the Pharmaceutical Industry

    2005 Invited Lecturer, School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC

    1997 Research distinction, Microbiology, Georgia State University, Atlanta, GA

Life Sciences
Communities:

Nader Moniri's Genealogy

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Nader Moniri's Publications (12)



Nader Moniri's Posters and Presentations (12)

  • Omega-3 fatty acid mediated phosphorylation of the short and long human GPR120 receptor isoforms (poster)

    Rebecca L. Burns and Nader H. Moniri

    Experimental Biology, Anaheim, CA; 04/2010
  • Regulation of beta-2-adrenergic receptor signaling by reactive oxygen species. (presentation)

    Nader H. Moniri

    Georgia State University, Dept of Biology, Seminar Series, Atlanta, GA; 12/2009
  • Beta-2-adrenergic receptor mediated generation of reactive oxygen species is a component required for signal transduction, desensitization, and homodimerization (poster)

    Nader H. Moniri and Yehia Daaka

    Experimental Biology, San Diego, CA; 04/2008
  • Cloning, expression, and initial functional characterization of the human and rat free-fatty acid receptor GPR120 (poster)

    Rebecca L. Burns, Mary A. Hendy, Nader H. Moniri

    ASPET - SE Region Annual Meeting, Augusta, GA; 02/2007
  • Functionally selective ligands for the Histamine H1 GPCR. (poster)

    Raymond G. Booth and Nader H. Moniri

    Experimental Biology, San Diego, CA; 04/2005
  • Functionally selective histamine H1 receptor ligands stimulate tyrosine hydroxylase in bovine adrenal chromaffin cells: effects of PKC and PKA inhibition on H1-mediated catecholamine synthesis (poster)

    Nader H. Moniri and Raymond G. Booth

    Society for Neuroscience, New Orleans, LA; 11/2003
  • (±)-2-Dimethylamino-5-phenyl-1,2,3,4- tetrahydronaphthalene binds to histamine H1 receptors and selectively modulates cAMP vs. IP signaling pathways (poster)

    Jacqueline Legere, Nader H. Moniri, Raymond G. Booth

    Amercian Chemical Society, New Orleans, LA; 03/2003
  • 2-Dimethylamino-5-phenyl-1,2,3,4-tetrahydronaphthalenes: A new class of ligands for histamine H1 and serotonin 5-HT2 type receptors. (poster)

    Jacqueline Leger, Nader H. Moniri, Raymond G. Booth

    American Chemical Society, New York, NY; 03/2003
  • Novel ligands selectively activate histamine H1 receptors coupled to IP vs. cAMP signaling pathways to stimulate tyrosine hydroxylase. (poster)

    Nader H. Moniri, Steven D. Wyrick, Raymond G. Booth

    Society for Neuroscience, Orlando, FL; 11/2002
  • Novel phenylaminotetralins stimulate IP accumulation and dopamine synthesis in rat striatum. (poster)

    Ola M. Ghoneim, Dawn W. Covington, Nader H. Moniri, Raymond G. Booth

    Society for Neuroscience, Orlando, FL; 11/2002
  • Novel phenylaminotetralins stimulate IP accumulation and dopamine synthesis in rat striatum. (poster)

    Ola M. Ghoneim, Dawn W. Covington, Nader H. Moniri, Raymond G. Booth

    Society for Neuroscience, Orlando, FL; 11/2002
  • New rigid diarylaminopropanes are histamine H1 ligands that stimulate brain dopamine synthesis (poster)

    Nader H. Moniri, Steven D. Wyrick, Raymond G. Booth

    Society for Neuroscience, San Diego, CA; 11/2001

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