Epernicus: Maithreye R, Ph.D.

Maithreye R, Ph.D.

Positions:
Post Doctoral Fellow

Biotechnology

CNS lab

Indian Institute of Technology,Madras

Unemployed

None
Advisor:
Srinivasa V Chakravarthy
Degrees:

Ph.D., Computational Biology, Centre for Cellular and Molecular Biology (Hyderabad, India)

M.Sc., Microbiology, University of Mumbai (Mumbai, India)
Past Advisors:

Somdatta Sinha (as Graduate Student - Ph.D.)
Research:
The objective of my present work is to create and study models of Basal ganglia function.

I am working on creating networks of spiking neurons of the different modules of the basal ganglia that incorporates accurate patterns of spiking and respond to input (neurotransmitters and neuromodulators) in a realistic fashion. I had also studied behavioural switching in the basal ganglia using saccadic eye movement and modelled the effect of learning in these networks based on the Reinforcement Learning (RL) paradigm.

Results: I have created and studied small networks of STN and GPe of simple Izhikevich type neurons and am working to improve and extend these models. I had also matched the results of my saccade models with the experimental literature and showed that the model is capable of learning task switching successfully.
Other Experience:
2007 Scientist in TCS, Hyderabad

Communities:

The Adobe Flash Player plugin (version 8) is required to view the genealogy tree.
Download the plugin here.

Modeling the role of basal ganglia in saccade generation: Is the indirect pathway the explorer?
Krishnan R, Ratnadurai S, Subramanian D, Chakravarthy VS, Rengaswamy M

Neural networks : the official journal of the International Neural Network Society. 2011 Oct;24(8):801-13
Expanding the Go/No-go depiction of the basal ganglia pathways
Sanjeev Kumar, Maithreye R, Neelima Gupte, Srinivasa V Chakravarthy

Proceedings of the 2011 International Joint Conference on Neural Networks (IJCNN 2011).. 2011
A study of the switching function of the Subthalamic Nucleus in saccade generation using a computational model of basal Ganglia,
Maithreye R, Srinivasa V Chakravarthy

Proceedings of the 2010 International Joint Conference on Neural Networks (IJCNN 2010). 2010
A study of the switching function of the Subthalamic Nucleus in saccade generation using a computational model of basal Ganglia,
Maithreye R, Srinivasa V Chakravarthy

Proceedings of the 2010 International Joint Conference on Neural Networks (IJCNN 2010). 2010
Delay-induced transient increase and heterogeneity in gene expression in negatively auto-regulated gene circuits.
Maithreye R, Sarkar RR, Parnaik VK, Sinha S

PloS one. 2008;3(8):e2972
Propagation of extrinsic perturbation in a negatively auto-regulated pathway.
Maithreye R, Sinha S

Physical biology. 2007 Mar;4(1):48-59

Modelling of simple biochemical networks (poster)
Maithreye R

Imaging, Modelling and Manipulation of Transcriptional Regulatory Networks; 10/2002
Modelling of Simple Biochemical Networks (poster)
Somdatta Sinha and Maithreye R

First International MT-Bio Conference on "Function and Regulation of Cellular systems: Experiments and Models ; 06/2001

Join Epernicus (membership is free)

Epernicus is open to current and former research scientists.

Already a member?
Sign in to view Maithreye's full profile.