Epernicus: Massimo Merighi, Ph.D.

Massimo Merighi, Ph.D.

Positions:
staff scientist

Microbial Metabolic Engineering

Glycosyn, Inc. (Medford, MA)

Research Fellow

Microbiology and Molecular Genetics

Harvard Medical School (Boston, MA)
Advisors:
John McCoy, Stephen Lory
Degrees:

Ph.D., Biotechnology/Bacteriology/Plant Pathology, The Ohio State University (Columbus, OH)
Past Advisors:

John S. Gunn (as Post Doctoral Fellow)

David L. Coplin (as Graduate Student - Ph.D.)
Research:
bacterial signal transduction and pathogenesis

Bacterial second messenger signaling, two-component signal transduction, chemical genetics in Pseudomonas aeruginosa.
Honors:
2002-2003 Presidential Fellow of The Ohio State University

Communities:

Massimo Merighi's Genealogy

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Massimo Merighi's Publications (11)

Direct interaction between sensor kinase proteins mediates acute and chronic disease phenotypes in a bacterial pathogen.
Goodman AL, Merighi M, Hyodo M, Ventre I, Filloux A, Lory S

Genes & development. 2009 Jan 15;23(2):249-59
Genome-wide analysis of the PreA/PreB (QseB/QseC) regulon of Salmonella enterica serovar Typhimurium.
Merighi M, Septer AN, Carroll-Portillo A, Bhatiya A, Porwollik S, McClelland M, Gunn JS

BMC microbiology. 2009;9:42
The second messenger bis-(3'-5')-cyclic-GMP and its PilZ domain-containing receptor Alg44 are required for alginate biosynthesis in Pseudomonas aeruginosa.
Merighi M, Lee VT, Hyodo M, Hayakawa Y, Lory S

Molecular microbiology. 2007 Aug;65(4):876-95
Molecular characterization of Pantoea stewartii subsp. stewartii HrpY, a conserved response regulator of the Hrp type III secretion system, and its interaction with the hrpS promoter.
Merighi M, Majerczak DR, Zianni M, Tessanne K, Coplin DL

Journal of bacteriology. 2006 Jul;188(14):5089-100
Identification of the DNA bases of a DNase I footprint by the use of dye primer sequencing on an automated capillary DNA analysis instrument.
Zianni M, Tessanne K, Merighi M, Laguna R, Tabita FR

Journal of biomolecular techniques : JBT. 2006 Apr;17(2):103-13
Role of Salmonella enterica serovar Typhimurium two-component system PreA/PreB in modulating PmrA-regulated gene transcription.
Merighi M, Carroll-Portillo A, Septer AN, Bhatiya A, Gunn JS

Journal of bacteriology. 2006 Jan;188(1):141-9
Resolvase-in vivo expression technology analysis of the Salmonella enterica serovar Typhimurium PhoP and PmrA regulons in BALB/c mice.
Merighi M, Ellermeier CD, Slauch JM, Gunn JS

Journal of bacteriology. 2005 Nov;187(21):7407-16
A novel transcriptional autoregulatory loop enhances expression of the Pantoea stewartii subsp. stewartii Hrp type III secretion system.
Merighi M, Majerczak DR, Coplin DL

FEMS microbiology letters. 2005 Feb 15;243(2):479-87
Identification of cptA, a PmrA-regulated locus required for phosphoethanolamine modification of the Salmonella enterica serovar typhimurium lipopolysaccharide core.
R Tamayo , B Choudhury , A Septer , M Merighi , R Carlson , J S Gunn

J Bacteriol. . 2005;187:3391-9
Chlamydomonas reinhardtii secretes compounds that mimic bacterial signals and interfere with quorum sensing regulation in bacteria.
Teplitski M, Chen H, Rajamani S, Gao M, Merighi M, Sayre RT, Robinson JB, Rolfe BG, Bauer WD

Plant physiology. 2004 Jan;134(1):137-46
The HrpX/HrpY two-component system activates hrpS expression, the first step in the regulatory cascade controlling the Hrp regulon in Pantoea stewartii subsp. stewartii.
Merighi M, Majerczak DR, Stover EH, Coplin DL

Molecular plant-microbe interactions : MPMI. 2003 Mar;16(3):238-48

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Massimo Merighi, Ph.D.

staff scientist

Research Fellow

bacterial signal transduction and pathogenesis

Massimo Merighi's Genealogy

Massimo Merighi's Publications (11)