Matthew I Hutchings

Matthew I Hutchings, Ph.D.

  • Position:
    Research Fellow

    School of Biological Sciences

    School of Medicine

    University of East Anglia (Norwich, UK)

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  • Degrees:
     
    Ph.D., Bacteriology, University of Southampton (Southampton, UK)
     
    B.Sc., Biology, University of Portsmouth (Portsmouth, UK)
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  • Past Advisors:
     
    Mark J Buttner (as Post Doctoral Fellow)
     
    Stephen Spiro (as Post Doctoral Fellow)
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  • Research:
    How bacteria sense and respond to environmental stress.

    Most of our work focuses on a genus of Gram-positive bacteria called Streptomyces. They are best known for producing useful secondary metabolites that have been exploited for human and animal medicine. They produce around two thirds of the commercially important antibiotics as well as compounds which are used to treat parasite and fungal infections and cancer. Streptomyces are also the source of most antibiotic resistance genes, which give them immunity to the antibiotics they produce. These antibiotic resistance genes are spreading rapidly to pathogenic bacteria like MRSA. Our major areas of interest are: Signal transduction; The bacterial cell envelope; The cell surface; Nitric oxide stress; Chromosome maintenance and repair.

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  • Other Experience:
Life Sciences
Communities:

Matthew Hutchings's Genealogy

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Matthew Hutchings's Publications (18)



One Figure

One Figure for Matthew I Hutchings

Streptomyces coelicolor overproducing the blue antibiotic actinorhodin


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