Epernicus: Michael E. Zwick, Ph.D.

Michael E. Zwick, Ph.D.

Position:
Assistant Professor

Human Genetics

Emory University (Atlanta, GA)
Degrees:

Ph.D., Population Biology, University of California, Davis (Davis, CA)

B.S., Genetics and Development, Cornell University (Ithaca, NY)
Past Advisors:

Aravinda Chakravarti (as Post Doctoral Fellow)

Charles Langley (as Graduate Student - Ph.D.)
Research:
Primary research focus included the detection and characterization of rare genetic variants contributing to common pediatric disorders.

Primary research focus included the detection and characterization of rare genetic variants contributing to common pediatric disorders. Projects include identifying X-linked autism susceptibility loci and exploring how copy number variation contributes to the risk of atrioventricular septal heart defects in Down Syndrome. Develop methods of targeted enrichment and bioinformatic tools necessary to pursue research projects. Elucidate the population genomics of biodefense pathogens.
Other Experience:
1989-present United States Navy

Communities:

Michael Zwick's Genealogy

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Michael Zwick's Publications (25)

Targeted sequencing of the human X chromosome exome.
Mondal K, Shetty AC, Patel V, Cutler DJ, Zwick ME

Genomics. 2011 Apr 16
Mutations in the human SC4MOL gene encoding a methyl sterol oxidase cause psoriasiform dermatitis, microcephaly, and developmental delay.
He M, Kratz LE, Michel JJ, Vallejo AN, Ferris L, Kelley RI, Hoover JJ, Jukic D, Gibson KM, Wolfe LA, Ramachandran D, Zwick ME, Vockley J

The Journal of clinical investigation. 2011 Mar 1;121(3):976-84
Microarray oligonucleotide probe designer (MOPeD): A web service.
Patel VC, Mondal K, Shetty AC, Horner VL, Bedoyan JK, Martin D, Caspary T, Cutler DJ, Zwick ME

Open access bioinformatics. 2010 Nov 1;2(2010):145-155
Identification of novel FMR1 variants by massively parallel sequencing in developmentally delayed males.
Collins SC, Bray SM, Suhl JA, Cutler DJ, Coffee B, Zwick ME, Warren ST

American journal of medical genetics. Part A. 2010 Oct;152A(10):2512-20
Copy number abnormalities in sporadic canine colorectal cancers.
Tang J, Le S, Sun L, Yan X, Zhang M, Macleod J, Leroy B, Northrup N, Ellis A, Yeatman TJ, Liang Y, Zwick ME, Zhao S

Genome research. 2010 Mar;20(3):341-50
Array-based FMR1 sequencing and deletion analysis in patients with a fragile X syndrome-like phenotype.
Collins SC, Coffee B, Benke PJ, Berry-Kravis E, Gilbert F, Oostra B, Halley D, Zwick ME, Cutler DJ, Warren ST

PloS one. 2010;5(3):e9476
Empirical evaluation of oligonucleotide probe selection for DNA microarrays.
Mulle JG, Patel VC, Warren ST, Hegde MR, Cutler DJ, Zwick ME

PloS one. 2010;5(3):e9921
Genomic characterization of the Yersinia genus.
Chen PE, Cook C, Stewart AC, Nagarajan N, Sommer DD, Pop M, Thomason B, Thomason MP, Lentz S, Nolan N, Sozhamannan S, Sulakvelidze A, Mateczun A, Du L, Zwick ME, Read TD

Genome biology. 2010;11(1):R1
Rapid identification of genetic modifications in Bacillus anthracis using whole genome draft sequences generated by 454 pyrosequencing.
Chen PE, Willner KM, Butani A, Dorsey S, George M, Stewart A, Lentz SM, Cook CE, Akmal A, Price LB, Keim PS, Mateczun A, Brahmbhatt TN, Bishop-Lilly KA, Zwick ME, Read TD, Sozhamannan S

PloS one. 2010;5(8):e12397
SeqAnt: a web service to rapidly identify and annotate DNA sequence variations.
Shetty AC, Athri P, Mondal K, Horner VL, Steinberg KM, Patel V, Caspary T, Cutler DJ, Zwick ME

BMC bioinformatics. 2010;11:471
Combining microarray-based genomic selection (MGS) with the Illumina Genome Analyzer platform to sequence diploid target regions.
Okou DT, Locke AE, Steinberg KM, Hagen K, Athri P, Shetty AC, Patel V, Zwick ME

Annals of human genetics. 2009 Sep;73(Pt 5):502-13
Structure and complexity of a bacterial transcriptome.
Passalacqua KD, Varadarajan A, Ondov BD, Okou DT, Zwick ME, Bergman NH

Journal of bacteriology. 2009 May;191(10):3203-11
Microarray-based mutation detection in the dystrophin gene.
Hegde MR, Chin EL, Mulle JG, Okou DT, Warren ST, Zwick ME

Human mutation. 2008 Sep;29(9):1091-9
Applying rapid genome sequencing technologies to characterize pathogen genomes.
Steinberg KM, Okou DT, Zwick ME

Analytical chemistry. 2008 Feb 1;80(3):520-8
Genotyping of Bacillus cereus strains by microarray-based resequencing.
Zwick ME, Kiley MP, Stewart AC, Mateczun A, Read TD

PloS one. 2008;3(7):e2513
Microarray-based genomic selection for high-throughput resequencing.
Okou DT, Steinberg KM, Middle C, Cutler DJ, Albert TJ, Zwick ME

Nature methods. 2007 Nov;4(11):907-9
A genome sequencing center in every lab.
Zwick ME

European journal of human genetics : EJHG. 2005 Nov;13(11):1167-8
Microarray-based resequencing of multiple Bacillus anthracis isolates.
Zwick ME, Mcafee F, Cutler DJ, Read TD, Ravel J, Bowman GR, Galloway DR, Mateczun A

Genome biology. 2005;6(1):R10
Discrepancies in dbSNP confirmation rates and allele frequency distributions from varying genotyping error rates and patterns.
Mitchell AA, Zwick ME, Chakravarti A, Cutler DJ

Bioinformatics (Oxford, England). 2004 May 1;20(7):1022-32
Haplotype inference in random population samples.
Lin S, Cutler DJ, Zwick ME, Chakravarti A

American journal of human genetics. 2002 Nov;71(5):1129-37
High-throughput variation detection and genotyping using microarrays.
Cutler DJ, Zwick ME, Carrasquillo MM, Yohn CT, Tobin KP, Kashuk C, Mathews DJ, Shah NA, Eichler EE, Warrington JA, Chakravarti A

Genome research. 2001 Nov;11(11):1913-25
Patterns of genetic variation in Mendelian and complex traits.
Zwick ME, Cutler DJ, Chakravarti A

Annual review of genomics and human genetics. 2000;1:387-407
Classic Weinstein: tetrad analysis, genetic variation and achiasmate segregation in Drosophila and humans.
Zwick ME, Cutler DJ, Langley CH

Genetics. 1999 Aug;152(4):1615-29
Genetic variation in rates of nondisjunction: association of two naturally occurring polymorphisms in the chromokinesin nod with increased rates of nondisjunction in Drosophila melanogaster.
Zwick ME, Salstrom JL, Langley CH

Genetics. 1999 Aug;152(4):1605-14
Mitochondrial DNA in the bark weevils: size, structure and heteroplasmy.
Boyce TM, Zwick ME, Aquadro CF

Genetics. 1989 Dec;123(4):825-36

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Michael E. Zwick, Ph.D.

Assistant Professor

Primary research focus included the detection and characterization of rare genetic variants contributing to common pediatric disorders.

Michael Zwick's Genealogy

Michael Zwick's Publications (25)

Websites