Marcel E Dinger

Marcel E Dinger, Ph.D.

  • Position:
    Senior Research Officer

    Division of Genomics and Computational Biology

    Institute for Molecular Bioscience (Brisbane, Australia)

  •  
  • Advisor:

    John S Mattick

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  • Degrees:
     
    Ph.D., Molecular Biology, University of Waikato (Hamilton, New Zealand)
     
    M.Sc., Genetics, University of Waikato (Hamilton, New Zealand)
     
    B.Sc., Biology, University of Waikato (Hamilton, New Zealand)
  •  
  • Past Advisors:
     
    David R. Musgrave (as Graduate Student - Ph.D.)
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  • Research:
    Functional examination of mammalian long noncoding RNAs

    The majority of the mammalian genome is transcribed as noncoding RNAs. Rather than being transcriptional artefact, we predict that many of these transcripts act as regulatory molecules. My research is focused on a subset of these transcripts referred to as long noncoding RNAs (ncRNAs). Although a small number have been shown to have function, it is not clear how many of the ~30,000 long ncRNAs that have been identified in mammals are also functional and whether these transcripts can be classified into functional subgroups. Using a combination of bioinformatic and genome-scale experimental approaches we hope to learn more about this part of the transcriptome.

  •  
  • Other Experience:

    2002-2006 Scientific Copyeditor, Codex Editing Services

    1999-2005 Director and co-founder, Genamics Ltd

    2001-2003 Assistant Lecturer, University of Waikato

    1996-2002 Tutor and Teaching Assistant, University of Waikato

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  • Honors:

    2010-present NHMRC Career Development Award

    2009-present Smart Futures Fellow

    2008 Fresh Scientist 2008

    2005-2008 Foundation of Research, Science and Technology New Zealand Postdoctoral Fellowship

    1999-2002 University of Waikato Ph.D. Scholarship

    1997-1998 University of Waikato Masters and Honours

Life Sciences
Communities:

Marcel Dinger's Genealogy

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Marcel Dinger's Publications (35)



Marcel Dinger's Posters and Presentations (29)

  • Leave no base unturned: Understanding human development and disease through an integrated analysis of gene regulatory architecture (presentation)

    Marcel E Dinger

    Children's Cancer Research Institute, Sydney, Australia; 03/2012
  • RNA Capture-Seq resolves the deep complexity of the human transcriptome (presentation)

    Marcel E Dinger

    Molecular Biology Society of Japan, Yokohama, Japan; 12/2011
  • The expanding functional repertoire of long noncoding RNAs (presentation)

    Marcel E Dinger

    Tokyo RNA Club, Tokyo, Japan; 12/2011
  • RNA Capture-Seq resolves the deep complexity of the human transcriptome (presentation)

    Marcel E Dinger

    Personal Genomes, Cold Spring Harbor Laboratories, New York, USA; 09/2011
  • Through a transcriptome, darkly: emergence of novel long noncoding RNAs in disease and development (presentation)

    Marcel E Dinger

    Murdoch Children's Research Institute, Melbourne, Australia; 08/2011
  • Through a transcriptome, darkly: emergence of novel RNAs in disease and development (presentation)

    Marcel E Dinger

    NSW miRNA Users Worksop, Sydney, Australia; 07/2011
  • The expanding functional repertoire of long noncoding RNAs (presentation)

    Marcel E Dinger

    Lorne Genome Conference 2011, Lorne, Australia; 02/2011
  • Long noncoding RNAs as biomarkers in breast cancer and melanoma (presentation)

    Marcel E Dinger

    Biomarker Discovery Conference, Shoal Bay, Australia; 12/2010
  • Noncoding RNAs: are these the missing regulators of disease? (presentation)

    Marcel E Dinger

    Biomarker Discovery Conference, Shoal Bay, Australia; 12/2010
  • Through the transcriptome, darkly: emergence of novel RNAs in disease and development (presentation)

    Marcel E Dinger

    Queensland Area RNA Club, QuARC, Brisbane, Australia; 10/2010
  • Characterization of long noncoding RNAs by ultra deep sequencing of the human transcriptome (presentation)

    Marcel E Dinger

    Australasian Microarray and Associated Technologies Association, AMATA, Hobart, Tasmania, Australia; 09/2010
  • Long noncoding RNAs: functional elements of the human transcriptome (presentation)

    Marcel E Dinger

    OzBio, Melbourne, Australia; 09/2010
  • Long noncoding RNAs: transcriptomic complexity and nomenclature (presentation)

    Marcel E Dinger

    Noncoding RNA Database Workshop, Wellcome Trust Genome Campus, Hinxton, England; 07/2010
  • The hippocampal expression of 31 noncoding RNAs is upregulated in Alzheimer’s Disease patients and three positively correlate with MMSE results and other biomarkers of disease progression (poster)

    Marcel E Dinger, Ahmed Shamsul Arefin, Regina Berretta, Pablo Moscato

    10th Alzheimer’s Association International Conference on Alzheimer’s Disease 2010, Honolulu, Hawaii; 07/2010
  • Long non-coding RNAs: Implications on development and disease (presentation)

    Marcel E Dinger

    School of Chemistry and Molecular Biosciences Seminar Series, University of Queensland, Brisbane, Australia; 05/2010
  • Long non-coding RNAs: Implications on genetics and disease (presentation)

    Marcel E Dinger

    10th Annual Meeting of the Belgian Society of Human Genetics, ICC, Ghent, Belgium; 02/2010
  • Long noncoding RNAs: Impact on development and disease (presentation)

    Marcel E Dinger

    Techniques in Cancer Genomics, VUMC, Amsterdam, The Netherlands; 02/2010
  • GWAS revisited: A new perspective on genome-wide association studies based on an empirical annotation of the coding and noncoding transcriptome (poster)

    Marcel E Dinger, Tim R Mercer, John S Mattick

    Lorne Genome Conference 2010, Lorne, Australia; 01/2010
  • Beyond the exome: Re-interpretation of genome-wide association studies using an empirically-based annotation of the noncoding transcriptome (presentation)

    Marcel E Dinger, Tim R Mercer, John S Mattick

    Australasian Microarray and Associated Technologies Association, AMATA, Katoomba NSW, Australia; 10/2009
  • Long noncoding RNA: insights into function (presentation)

    Marcel E Dinger, Tim R Mercer, Paulo P Amaral, Ken C Pang, Susan M Sunkin, Andrew C Perkins, John S Mattick

    Marie Curie Genome Architecture in Relation to Disease: Higher Order Genome Architecture, Edinburgh, Scotland; 04/2009
  • The eukaryotic genome as an RNA machine (presentation)

    Marcel E Dinger, Tim R Mercer, Paulo P Amaral, Ken C Pang, Susan M Sunkin, Mark F Mehler, Andrew C Perkins, John S Mattick

    Marie Curie Genome Architecture in Relation to Disease: Genome Bioinformatic Techniques, Braga, Portugal; 09/2008
  • Using bioinformatics to predict the function of noncoding RNAs (presentation)

    Marcel E Dinger

    Marie Curie Genome Architecture in Relation to Disease: Genome Bioinformatic Technique, Braga, Portugal; 09/2008
  • Long noncoding RNAs in the central nervous system (poster)

    Marcel E Dinger, Tim R Mercer, Paulo P Amaral, Susan M Sunkin, Mark F Mehler, John S Mattick

    Keystone Symposium: RNAi, MicroRNA, and Non-Coding RNA, Whistler BC, Canada; 03/2008
  • Long noncoding RNAs in mammalian differentiation and development (presentation)

    Marcel E Dinger

    Centenary Colloquium IV: Opportunities in RNA-based Therapeutics, Sydney, Australia; 01/2008
  • An automated approach to identify and annotate long noncoding transcripts for functional study (presentation)

    Marcel E Dinger, Tim R Mercer, John S Mattick

    Bioinformatics Australia, Brisbane, Australia; 10/2007
  • Dynamic expression of long noncoding RNAs during mouse embryonic stem cell differentiation (poster)

    Marcel E Dinger, Ken C Pang, Tim R Mercer, Giulia Soldà, Paulo P Amaral, Stephen Bruce, Brooke B Gardiner, Andrew C Perkins, Sean M Grimmond, Susan M Sunkin, John S Mattick

    International Society for Stem Cell Research, Cairns QLD, Australia; 06/2007
  • Tissue- and developmentally-specific expression of long noncoding RNA in mouse (presentation)

    Marcel E Dinger

    Brisbane Stem Cell Forum, Brisbane, Australia; 05/2007
  • Dynamic expression of ncRNAs during mammalian differentiation and development (presentation)

    Marcel E Dinger, Ken C Pang, Stephen Bruce, Andrew C Perkins, Sean M Grimmond, John S Mattick

    ComBio2006, Brisbane, Australia; 09/2006
  • Identification of differentially expressed ncRNAs involved in myoblast differentiation using a novel ncRNA microarray (poster)

    Marcel E Dinger, Evgeny Glazov, Ken C Pang, Mark Crowe, John S Mattick

    Lorne Genome 2006, Lorne VIC, Australia; 02/2006

One Figure

One Figure for Marcel E Dinger

Transcriptomic complexity of the mammalian genome. Long noncoding RNAs are associated with many protein-coding genes and may be involved in regulating their expression.


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