Epernicus: Manuel Ascano Jr, Ph.D.

Manuel Ascano Jr, Ph.D.

Position:
Post Doctoral Fellow

RNA Molecular Biology

The Rockefeller University (New York, NY)
Advisor:
Thomas Tuschl
Degrees:

Ph.D., Molecular Genetics, Biochemistry and Microbiology, University of Cincinnati College of Medicine (Cincinnati, OH), Dartmouth Medical School (Hanover, NH)
Past Advisors:
Research:

Communities:

Manuel Ascano Jr's Genealogy

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Manuel Ascano Jr's Publications (8)

Costal2 Functions as a Kinesin-like Protein in the Hedgehog Signal Transduction Pathway.
Farzan SF, Ascano M, Ogden SK, Sanial M, Brigui A, Plessis A, Robbins DJ

Current biology : CB. 2008 Aug 6
Smoothened regulates activator and repressor functions of Hedgehog signaling via two distinct mechanisms.
Ogden SK, Casso DJ, Ascano M, Yore MM, Kornberg TB, Robbins DJ

The Journal of biological chemistry. 2006 Mar 17;281(11):7237-43
An intramolecular association between two domains of the protein kinase Fused is necessary for Hedgehog signaling.
Ascano M, Robbins DJ

Molecular and cellular biology. 2004 Dec;24(23):10397-405
Regulation of Hedgehog signaling: a complex story.
Ogden SK, Ascano M, Stegman MA, Robbins DJ

Biochemical pharmacology. 2004 Mar 1;67(5):805-14
The Kinesin-related protein Costal2 associates with membranes in a Hedgehog-sensitive, Smoothened-independent manner.
Stegman MA, Goetz JA, Ascano M, Ogden SK, Nybakken KE, Robbins DJ

The Journal of biological chemistry. 2004 Feb 20;279(8):7064-71
Identification of a functional interaction between the transmembrane protein Smoothened and the kinesin-related protein Costal2.
Ogden SK, Ascano M, Stegman MA, Suber LM, Hooper JE, Robbins DJ

Current biology : CB. 2003 Nov 11;13(22):1998-2003
The carboxyl-terminal domain of the protein kinase fused can function as a dominant inhibitor of hedgehog signaling.
Ascano M, Nybakken KE, Sosinski J, Stegman MA, Robbins DJ

Molecular and cellular biology. 2002 Mar;22(5):1555-66
Conditions for vigorous growth on sulfide and reactor-scale cultivation protocols for the thermophilic green sulfur bacterium chlorobium tepidum
Mukhopadhyay B, Johnson EF, Ascano M

Appl Environ Microbiol. 1999 Jan;65(1):301-6

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Manuel Ascano Jr, Ph.D.

Post Doctoral Fellow

Manuel Ascano Jr's Genealogy

Manuel Ascano Jr's Publications (8)