Long Ma

Long Ma, Ph.D.

  • Position:
    Post Doctoral Fellow

    Biology

    Massachusetts Institute of Technology (Cambridge, MA)

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  • Advisor:

    H. Robert Horvitz

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  • Degrees:
     
    Ph.D., Genetics and Development, University of Texas Southwestern Medical Center (Dallas, TX)
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  • Past Advisors:
     
    Luis F. Parada (as Post Doctoral Fellow)
     
    Luis F. Parada (as Graduate Student - Ph.D.)
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  • Research:
    Molecular genetic analysis of pre-mRNA splicing and functional
    study of a two-pore potassium channel complex in C. elegans.

    I use genetics, molecular biology, biochemistry and other relevant methods to understand the genetic interactions and signaling events that lead to alternative splicing. I currently focus on two critical splicing factors, the U2AF large subunit and SF1/BBP, and a conserved nuclear protein with unknown functions that interacts with the U2AF large subunit. I also try to understand the function of a two-pore domain potassium channel complex comprised of UNC-93, SUP-9 and SUP-10 with genetics and behavioral analysis. A mammalian homolog of UNC-93 is critical for innate immune response to virus infection. Therefore my study about the C. elegans ortholog may further the understanding about the human protein.

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Life Sciences
Communities:

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