Committee on the Neurobiology of Addictive Disorders
The Scripps Research Institute (La Jolla, CA)
Food intake and energy balance are regulated by the complex interplay of a series of neurotransmitters, neuromodulators, and neuropeptides. The complexity of this highly-evolved and multiply-redundant system may well reflect the physiological importance of feeding behavior. Obviously, an organism that cannot control food intake and regulate metabolism does not persist long enough to reproduce and therefore represents an evolutionary dead end. The central focus of my research is the interaction between cannabinergic drugs and diets rich in omega-6 polyunsaturated fatty acids. An emerging body of evidence suggests that sustained consumption of diets rich in omega-6 polyunsaturated fatty acids (e.g., the typical Western diet) reduces CB1 receptor expression in a region-specific fashion and reduces the sensitivity to some of the pharmacological effects of cannabinergic drugs.
2009-present NIAAA Institutional Training Grant
2008 NIDA/NIAAA/American Psychological Association Travel Award
2006-2009 National Institute on Drug Abuse Institutional Training Grant
2006-2008 International Cannabinoid Research Society Travel Grant

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M. Jerry Wright Jr, Renee Croce and Michael A Taffe
M. Jerry Wright Jr and Michael A Taffe
M. Jerry Wright Jr and Michael A Taffe
M. Jerry Wright Jr, Sophia A Davis, Glen D Dickinson, Michael A Taffe
M. Jerry Wright Jr and Jenny L Wiley
M. Jerry Wright Jr. & Jenny L. Wiley
M. Jerry Wright Jr. & Jenny L. Wiley
M. Jerry Wright Jr., James J. Burston, Darnica C. Leggettt, Raj K. Razdan & Jenny L. Wiley
M. Jerry Wright Jr., Mary E. Tokarz, Mary M. O'Connell & Jenny L Wiley