Jared M Schrader

Jared M Schrader, B.S.

  • Position:
    Graduate Student - Ph.D.

    Northwestern University (Evanston, IL)

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  • Advisor:

    Olke C. Uhlenbeck

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  • Degrees:
     
    B.S., Microbiology, Colorado State University - Fort Collins (Fort Collins, CO)
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  • Past Advisors:
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  • Research:
    Understanding how tRNAs are tuned to EF-Tu in translation

    In the elongation phase of translation, EF-Tu rapidly binds and delivers aminoacyl-tRNAs to the ribosome to ensure accurate and efficient incorporation. However, EF-Tu is a sequence specific binding protein and binds tRNAs with a 3.6 kcal/mol range in affinities. I have determined the sequence rules of tRNA binding to EF-Tu, and I am currently investigating the effects of modulating affinity of tRNAs to EF-Tu on their ability to incorporate.

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Life Sciences
Communities:

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Jared Schrader's Publications (1)



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