Jimmy C Lin
- Position:
MD/PhD Candidate
Johns Hopkins School of Medicine (Baltimore, MD)
- Advisor:
- Degrees:
- Past Advisors:
- Research:
Jimmy Lin's Genealogy
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Jimmy Lin's Publications (39)
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Exome sequencing identifies GRIN2A as frequently mutated in melanoma.
Wei X, Walia V, Lin JC, Teer JK, Prickett TD, Gartner J, Davis S, Stemke-Hale K, Davies MA, Gershenwald JE, Robinson W, Robinson S, Rosenberg SA, Samuels Y
Nature genetics. 2011 Apr 15 -
The genetic landscape of the childhood cancer medulloblastoma.
Parsons DW, Li M, Zhang X, Jones S, Leary RJ, Lin JC, Boca SM, Carter H, Samayoa J, Bettegowda C, Gallia GL, Jallo GI, Binder ZA, Nikolsky Y, Hartigan J, Smith DR, Gerhard DS, Fults DW, VandenBerg S, Berger MS, Marie SK, Shinjo SM, Clara C, Phillips PC, Minturn JE, Biegel JA, Judkins AR, Resnick AC, Storm PB, Curran T, He Y, Rasheed BA, Friedman HS, Keir ST, McLendon R, Northcott PA, Taylor MD, Burger PC, Riggins GJ, Karchin R, Parmigiani G, Bigner DD, Yan H, Papadopoulos N, Vogelstein B, Kinzler KW, Velculescu VE
Science (New York, N.Y.). 2011 Jan 28;331(6016):435-9 -
Mutational and functional analysis reveals ADAMTS18 metalloproteinase as a novel driver in melanoma.
Wei X, Prickett TD, Viloria CG, Molinolo A, Lin JC, Cardenas-Navia I, Cruz P, Rosenberg SA, Davies MA, Gershenwald JE, López-Otín C, Samuels Y
Molecular cancer research : MCR. 2010 Nov;8(11):1513-25 -
Novel somatic mutations in heterotrimeric G proteins in melanoma.
Cárdenas-Navia LI, Cruz P, Lin JC, Rosenberg SA, Samuels Y
Cancer biology & therapy. 2010 Jul;10(1):33-7 -
Understanding protein phosphorylation on a systems level.
Lin J, Xie Z, Zhu H, Qian J
Briefings in functional genomics. 2010 Jan;9(1):32-42 -
Protein microarrays for cancer diagnostics and therapy.
Medical principles and practice : international journal of the Kuwait University, Health Science Centre. 2010;19(4):247-54
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Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4.
Prickett TD, Agrawal NS, Wei X, Yates KE, Lin JC, Wunderlich JR, Cronin JC, Cruz P, Rosenberg SA, Samuels Y
Nature genetics. 2009 Oct;41(10):1127-32 -
Profiling the human protein-DNA interactome reveals ERK2 as a transcriptional repressor of interferon signaling.
Hu S, Xie Z, Onishi A, Yu X, Jiang L, Lin J, Rho HS, Woodard C, Wang H, Jeong JS, Long S, He X, Wade H, Blackshaw S, Qian J, Zhu H
Cell. 2009 Oct 30;139(3):610-22 -
Frequent mutations in the MITF pathway in melanoma.
Cronin JC, Wunderlich J, Loftus SK, Prickett TD, Wei X, Ridd K, Vemula S, Burrell AS, Agrawal NS, Lin JC, Banister CE, Buckhaults P, Rosenberg SA, Bastian BC, Pavan WJ, Samuels Y
Pigment cell & melanoma research. 2009 Aug;22(4):435-44 -
Relating periodicity of nucleosome organization and gene regulation.
Wan J, Lin J, Zack DJ, Qian J
Bioinformatics (Oxford, England). 2009 Jul 15;25(14):1782-8 -
SMAD4 gene mutations are associated with poor prognosis in pancreatic cancer.
Blackford A, Serrano OK, Wolfgang CL, Parmigiani G, Jones S, Zhang X, Parsons DW, Lin JC, Leary RJ, Eshleman JR, Goggins M, Jaffee EM, Iacobuzio-Donahue CA, Maitra A, Cameron JL, Olino K, Schulick R, Winter J, Herman JM, Laheru D, Klein AP, Vogelstein B, Kinzler KW, Velculescu VE, Hruban RH
Clinical cancer research : an official journal of the American Association for Cancer Research. 2009 Jul 15;15(14):4674-9 -
Analysis of the matrix metalloproteinase family reveals that MMP8 is often mutated in melanoma.
Palavalli LH, Prickett TD, Wunderlich JR, Wei X, Burrell AS, Porter-Gill P, Davis S, Wang C, Cronin JC, Agrawal NS, Lin JC, Westbroek W, Hoogstraten-Miller S, Molinolo AA, Fetsch P, Filie AC, O'Connell MP, Banister CE, Howard JD, Buckhaults P, Weeraratna AT, Brody LC, Rosenberg SA, Samuels Y
Nature genetics. 2009 May;41(5):518-20 -
Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene.
Jones S, Hruban RH, Kamiyama M, Borges M, Zhang X, Parsons DW, Lin JC, Palmisano E, Brune K, Jaffee EM, Iacobuzio-Donahue CA, Maitra A, Parmigiani G, Kern SE, Velculescu VE, Kinzler KW, Vogelstein B, Eshleman JR, Goggins M, Klein AP
Science (New York, N.Y.). 2009 Apr 10;324(5924):217 -
Genetic mutations associated with cigarette smoking in pancreatic cancer.
Blackford A, Parmigiani G, Kensler TW, Wolfgang C, Jones S, Zhang X, Parsons DW, Lin JC, Leary RJ, Eshleman JR, Goggins M, Jaffee EM, Iacobuzio-Donahue CA, Maitra A, Klein A, Cameron JL, Olino K, Schulick R, Winter J, Vogelstein B, Velculescu VE, Kinzler KW, Hruban RH
Cancer research. 2009 Apr 15;69(8):3681-8 -
Design and analysis issues in genome-wide somatic mutation studies of cancer.
Parmigiani G, Boca S, Lin J, Kinzler KW, Velculescu V, Vogelstein B
Genomics. 2009 Jan;93(1):17-21 -
Identification of microbial DNA in human cancer.
Duncan CG, Leary RJ, Lin JC, Cummins J, Di C, Schaefer CF, Wang TL, Riggins GJ, Edwards J, Bigner D, Kopelovich L, Vogelstein B, Kinzler KW, Velculescu VE, Yan H
BMC medical genomics. 2009;2:22 -
Analysis of regulatory network topology reveals functionally distinct classes of microRNAs.
Yu X, Lin J, Zack DJ, Mendell JT, Qian J
Nucleic acids research. 2008 Nov;36(20):6494-503 -
Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers.
Leary RJ, Lin JC, Cummins J, Boca S, Wood LD, Parsons DW, Jones S, Sjöblom T, Park BH, Parsons R, Willis J, Dawson D, Willson JK, Nikolskaya T, Nikolsky Y, Kopelovich L, Papadopoulos N, Pennacchio LA, Wang TL, Markowitz SD, Parmigiani G, Kinzler KW, Vogelstein B, Velculescu VE
Proceedings of the National Academy of Sciences of the United States of America. 2008 Oct 21;105(42):16224-9 -
An integrated genomic analysis of human glioblastoma multiforme.
Parsons DW, Jones S, Zhang X, Lin JC, Leary RJ, Angenendt P, Mankoo P, Carter H, Siu IM, Gallia GL, Olivi A, McLendon R, Rasheed BA, Keir S, Nikolskaya T, Nikolsky Y, Busam DA, Tekleab H, Diaz LA, Hartigan J, Smith DR, Strausberg RL, Marie SK, Shinjo SM, Yan H, Riggins GJ, Bigner DD, Karchin R, Papadopoulos N, Parmigiani G, Vogelstein B, Velculescu VE, Kinzler KW
Science (New York, N.Y.). 2008 Sep 26;321(5897):1807-12 -
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses.
Jones S, Zhang X, Parsons DW, Lin JC, Leary RJ, Angenendt P, Mankoo P, Carter H, Kamiyama H, Jimeno A, Hong SM, Fu B, Lin MT, Calhoun ES, Kamiyama M, Walter K, Nikolskaya T, Nikolsky Y, Hartigan J, Smith DR, Hidalgo M, Leach SD, Klein AP, Jaffee EM, Goggins M, Maitra A, Iacobuzio-Donahue C, Eshleman JR, Kern SE, Hruban RH, Karchin R, Papadopoulos N, Parmigiani G, Vogelstein B, Velculescu VE, Kinzler KW
Science (New York, N.Y.). 2008 Sep 26;321(5897):1801-6 -
Molecular profiling in the age of cancer genomics.
Lin J, Li M
Expert review of molecular diagnostics. 2008 May;8(3):263-76 -
The genomic landscapes of human breast and colorectal cancers.
Wood LD, Parsons DW, Jones S, Lin J, Sjöblom T, Leary RJ, Shen D, Boca SM, Barber T, Ptak J, Silliman N, Szabo S, Dezso Z, Ustyanksky V, Nikolskaya T, Nikolsky Y, Karchin R, Wilson PA, Kaminker JS, Zhang Z, Croshaw R, Willis J, Dawson D, Shipitsin M, Willson JK, Sukumar S, Polyak K, Park BH, Pethiyagoda CL, Pant PV, Ballinger DG, Sparks AB, Hartigan J, Smith DR, Suh E, Papadopoulos N, Buckhaults P, Markowitz SD, Parmigiani G, Kinzler KW, Velculescu VE, Vogelstein B
Science (New York, N.Y.). 2007 Nov 16;318(5853):1108-13 -
A multidimensional analysis of genes mutated in breast and colorectal cancers.
Lin J, Gan CM, Zhang X, Jones S, Sjöblom T, Wood LD, Parsons DW, Papadopoulos N, Kinzler KW, Vogelstein B, Parmigiani G, Velculescu VE
Genome research. 2007 Sep;17(9):1304-18 -
Genome-wide mutational analyses of breast and colorectal cancers.
Lin J, Sjöblom T
Discovery medicine. 2007 Feb;7(37):13-9 -
Systems biology approach to integrative comparative genomics.
Lin J, Qian J
Expert review of proteomics. 2007 Feb;4(1):107-19
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