Epernicus: Irwin Chen, Ph.D.

Irwin Chen, Ph.D.

Position:
Post Doctoral Fellow

Chemistry and Chemical Biology

Harvard University (Cambridge, MA)
Advisor:
David R Liu
Degrees:

Ph.D., Biological Chemistry, Massachusetts Institute of Technology (Cambridge, MA)

M.S., Chemistry, Stanford University (Stanford, CA)

A.B., Chemistry, Harvard University (Cambridge, MA)
Past Advisors:

Alice Y Ting (as Graduate Student - Ph.D.)

Barry M Trost (as Graduate Student - Masters)
Research:
Honors:
2008-present National Institutes of Health NRSA postdoctoral fellowship

2004-2005 American Chemical Society Division of Organic Chemistry Fellowship

2001-2004 National Science Foundation Graduate Research Fellowship

Communities:

Irwin Chen's Genealogy

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Irwin Chen's Publications (8)

Site-specific Modification of AAV Vector Particles With Biophysical Probes and Targeting Ligands Using Biotin Ligase.
Stachler MD, Chen I, Ting AY, Bartlett JS

Molecular therapy : the journal of the American Society of Gene Therapy. 2008 Jun 17
Expanding the substrate tolerance of biotin ligase through exploration of enzymes from diverse species.
Slavoff SA, Chen I, Choi YA, Ting AY

Journal of the American Chemical Society. 2008 Jan 30;130(4):1160-2
Phage display evolution of a peptide substrate for yeast biotin ligase and application to two-color quantum dot labeling of cell surface proteins.
Chen I, Choi YA, Ting AY

Journal of the American Chemical Society. 2007 May 23;129(20):6619-25
Synthesis of a ketone analogue of biotin via the intramolecular Pauson-Khand reaction.
McNeill E, Chen I, Ting AY

Organic letters. 2006 Sep 28;8(20):4593-5
Site-specific labeling of cell surface proteins with biophysical probes using biotin ligase.
Chen I, Howarth M, Lin W, Ting AY

Nature methods. 2005 Feb;2(2):99-104
Site-specific labeling of proteins with small molecules in live cells.
Chen I, Ting AY

Current opinion in biotechnology. 2005 Feb;16(1):35-40
A short and concise asymmetric synthesis of hamigeran B.
Trost BM, Pissot-Soldermann C, Chen I

Chemistry (Weinheim an der Bergstrasse, Germany). 2005 Jan 21;11(3):951-9
An asymmetric synthesis of hamigeran B via a Pd asymmetric allylic alkylation for enantiodiscrimination.
Trost BM, Pissot-Soldermann C, Chen I, Schroeder GM

Journal of the American Chemical Society. 2004 Apr 14;126(14):4480-1

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Irwin Chen, Ph.D.

Post Doctoral Fellow

Irwin Chen's Genealogy

Irwin Chen's Publications (8)