Epernicus: Felipe Cava, Ph.D.

Felipe Cava, Ph.D.

Position:
Postdoctoral Fellow

Medicine

Brigham and Women's Hospital (Boston, MA)
Advisor:
Matthew K. Waldor
Degrees:

Ph.D., Microbiology, Autonomous University of Madrid (Madrid, Spain)
Past Advisors:

José Berenguer (as Graduate Student - Ph.D.)

Sergei Borukhov (as Visiting Student)

Francis Blasco (as Visiting Student)
Research:
Determinants of Vibrio cholerae cell shape

My studies are aimed at identifying the molecular mechanisms and protein morphogens that govern cell shape determination and maintenance in V. cholerae. Furthermore, I plan to investigate if and how cell shape influences V. cholerae pathogenicity.
Honors:
2008 please, check my CV

Communities:

Felipe Cava's Genealogy

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Felipe Cava's Publications (20)

A cytochrome c containing nitrate reductase plays a role in electron transport for denitrification in Thermus thermophilus without involvement of the bc respiratory complex.
Cava F, Zafra O, Berenguer J

Molecular microbiology. 2008 Aug 29
Immobilization-stabilization of a new recombinant glutamate dehydrogenase from Thermus thermophilus.
Bolivar JM, Cava F, Mateo C, Rocha-Martín J, Guisán JM, Berenguer J, Fernandez-Lafuente R

Applied microbiology and biotechnology. 2008 Aug;80(1):49-58
Expression and use of superfolder green fluorescent protein at high temperatures in vivo: a tool to study extreme thermophile biology.
Cava F, de Pedro MA, Blas-Galindo E, Waldo GS, Westblade LF, Berenguer J

Environmental microbiology. 2008 Mar;10(3):605-13
The role of the nitrate respiration element of Thermus thermophilus in the control and activity of the denitrification apparatus.
Cava F, Zafra O, da Costa MS, Berenguer J

Environmental microbiology. 2008 Feb;10(2):522-33
An activity-independent selection system of thermostable protein variants.
Chautard H, Blas-Galindo E, Menguy T, Grand'Moursel L, Cava F, Berenguer J, Delcourt M

Nature methods. 2007 Nov;4(11):919-21
Use of a dominant rpsL allele conferring streptomycin dependence for positive and negative selection in Thermus thermophilus.
Blas-Galindo E, Cava F, López-Viñas E, Mendieta J, Berenguer J

Applied and environmental microbiology. 2007 Aug;73(16):5138-45
Control of the respiratory metabolism of Thermus thermophilus by the nitrate respiration conjugative element NCE.
Cava F, Laptenko O, Borukhov S, Chahlafi Z, Blas-Galindo E, Gómez-Puertas P, Berenguer J

Molecular microbiology. 2007 May;64(3):630-46
pH-dependent conformational switch activates the inhibitor of transcription elongation.
Laptenko O, Kim SS, Lee J, Starodubtseva M, Cava F, Berenguer J, Kong XP, Borukhov S

The EMBO journal. 2006 May 17;25(10):2131-41
Biochemical and regulatory properties of a respiratory island encoded by a conjugative plasmid in the extreme thermophile Thermus thermophilus.
Cava F, Berenguer J

Biochemical Society transactions. 2006 Feb;34(Pt 1):97-100
Membrane-associated maturation of the heterotetrameric nitrate reductase of Thermus thermophilus.
Zafra O, Cava F, Blasco F, Magalon A, Berenguer J

Journal of bacteriology. 2005 Jun;187(12):3990-6
Use of an antisense RNA strategy to investigate the functional significance of Mn-catalase in the extreme thermophile Thermus thermophilus.
Moreno R, Hidalgo A, Cava F, Fernández-Lafuente R, Guisán JM, Berenguer J

Journal of bacteriology. 2004 Nov;186(22):7804-6
A new type of NADH dehydrogenase specific for nitrate respiration in the extreme thermophile Thermus thermophilus.
Cava F, Zafra O, Magalon A, Blasco F, Berenguer J

The Journal of biological chemistry. 2004 Oct 29;279(44):45369-78
Thermus thermophilus as a cell factory for the production of a thermophilic Mn-dependent catalase which fails to be synthesized in an active form in Escherichia coli.
Hidalgo A, Betancor L, Moreno R, Zafra O, Cava F, Fernández-Lafuente R, Guisán JM, Berenguer J

Applied and environmental microbiology. 2004 Jul;70(7):3839-44
Binding to pyruvylated compounds as an ancestral mechanism to anchor the outer envelope in primitive bacteria.
Cava F, de Pedro MA, Schwarz H, Henne A, Berenguer J

Molecular microbiology. 2004 May;52(3):677-90
Enhancement of DNA, cDNA synthesis and fidelity at high temperatures by a dimeric single-stranded DNA-binding protein.
Perales C, Cava F, Meijer WJ, Berenguer J

Nucleic acids research. 2003 Nov 15;31(22):6473-80
Development of a gene expression vector for Thermus thermophilus based on the promoter of the respiratory nitrate reductase.
Moreno R, Zafra O, Cava F, Berenguer J

Plasmid. 2003 Jan;49(1):2-8
Dos Décadas de Helicobacter pylori
Felipe Cava, Guillermo Cobas

Vaccimonitor. 2003;12(1)
Formas cocoides de Helicobacter pylori: viables o degenerativas
Felipe Cava, Guillermo Cobas

Vaccimonitor. 2003;12(2)
A cytochrome c encoded by the nar operon is required for the synthesis of active respiratory nitrate reductase in Thermus thermophilus.
Zafra O, Ramírez S, Castán P, Moreno R, Cava F, Vallés C, Caro E, Berenguer J

FEBS letters. 2002 Jul 17;523(1-3):99-102
The periplasmic space in Thermus thermophilus: evidence from a regulation-defective S-layer mutant overexpressing an alkaline phosphatase.
Castán P, Zafra O, Moreno R, de Pedro MA, Vallés C, Cava F, Caro E, Schwarz H, Berenguer J

Extremophiles : life under extreme conditions. 2002 Jun;6(3):225-32

Felipe Cava's Posters and Presentations (1)

please, check my CV (poster)
Felipe Cava

-; 07/2008

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Felipe Cava, Ph.D.

Postdoctoral Fellow

Determinants of Vibrio cholerae cell shape

Felipe Cava's Genealogy

Felipe Cava's Publications (20)

Felipe Cava's Posters and Presentations (1)