Epernicus: D Randy Kipp, Ph.D.

D Randy Kipp, Ph.D.

Position:
Research Associate

Biochemistry

Albert Einstein College of Medicine (Bronx, New York)
Advisor:
Vern L Schramm
Degrees:

Ph.D., Biochemistry, Albert Einstein College of Medicine (Bronx, New York)

M.S., Biochemistry, Albert Einstein College of Medicine (Bronx, New York)

B.A., Molecular, Cellular, and Developmental Biology, University of Colorado (Boulder, CO)

B.A., Biochemistry, University of Colorado (Boulder, CO)
Past Advisors:

Vern L Schramm (as Graduate Student - Ph.D.)

Christopher D. Link (as Technician)

Christopher D. Link (as Undergraduate Student)
Research:
1. Transition state analysis of enzymatic reactions; 2. Exploring the role of enzyme dynamics in catalysis.

Communities:

D Randy Kipp's Genealogy

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D Randy Kipp's Publications (3)

Transition states of native and drug-resistant HIV-1 protease are the same.
Kipp DR, Hirschi JS, Wakata A, Goldstein H, Schramm VL

Proceedings of the National Academy of Sciences of the United States of America. 2012 Apr 24;109(17):6543-8
Mass-dependent bond vibrational dynamics influence catalysis by HIV-1 protease.
Kipp DR, Silva RG, Schramm VL

Journal of the American Chemical Society. 2011 Dec 7;133(48):19358-61
Suppression of in vivo beta-amyloid peptide toxicity by overexpression of the HSP-16.2 small chaperone protein.
Fonte V, Kipp DR, Yerg J, Merin D, Forrestal M, Wagner E, Roberts CM, Link CD

The Journal of biological chemistry. 2008 Jan 11;283(2):784-91

D Randy Kipp's Posters and Presentations (8)

Fast Timescale Dynamics of HIV-1 Protease in Catalysis (presentation)
D. Randal Kipp

Gordon Research Seminar, Isotopes in Biological & Chemical Sciences (Galveston, TX); 02/2012
Transition States and Dynamics of HIV-1 Protease (poster)
D. Randal Kipp, Jennifer S. Hirschi, Rafael G. Silve, Aya Wakata, Harris Goldstein, Vern L. Schramm

Gordon Research Conference, Isotopes in Biological & Chemical Sciences (Galveston, TX); 02/2012
Sub-Picosecond Timescale Dynamics of HIV-1 Protease Influence its Catalytic Efficiency (poster)
D. Randal Kipp, Rafael G. Silve, Vern L. Schramm

Engineering Conferences International, Enzyme Engineering (Vail, CO); 09/2011
Exploring the Role of Sub-picosecond Dynamics on Conformational Flexibility and Barrier Crossing in HIV-1 Protease (poster)
D. Randal Kipp, Rafael G. Silve, Vern L. Schramm

Gordon Research Conference, Enzymes, Coenzymes, and Metabolic Pathways (Waterville Valley, NH); 07/2011
HIV-1 Protease: Transition State Structures and Inhibitor Analysis (poster)
D. Randal Kipp, Jennifer S. Hirschi, Aya Wakata, Harris Goldstein, Vern L. Schramm

Gordon Research Conference, Enzymes, Coenzymes, and Metabolic Pathways (Waterville Valley, NH); 07/2010
Transition States of HIV-1 Protease (poster)
D. Randal Kipp, Jennifer S. Hirschi, Aya Wakata, Harris Goldstein, Vern L. Schramm

Gordon Research Conference, Proteolytic Enzymes and Their Inhibitors (Lucca, Italy); 05/2010
Transition State Analysis of Native and Drug Resistant HIV-1 Protease (poster)
D. Randal Kipp, Jennifer S. Hirschi, Aya Wakata, Harris Goldstein, Vern L. Schramm

Gordon Research Conference, Isotopes in Biological & Chemical Sciences (Galveston, TX); 02/2010
Kinetic Isotope Effect Analysis of Native and Drug Resistant HIV-1 Protease (poster)
D. Randal Kipp, Aya Wakata, Emilie Wang, Jennifer S. Hirschi, Harris Goldstein, Vern L. Schramm

Gordon Research Conference, Enzymes, Coenzymes & Metabolic Pathways (Waterville Valley, NH); 07/2009

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