Epernicus: David C Zappulla, Ph.D.

David C Zappulla, Ph.D.

Position:
Assistant Professor

Biology

Johns Hopkins University (Baltimore, MD)
Degrees:

Ph.D., Molecular and Cellular Biology, Stony Brook University (Stony Brook, NY)
Past Advisors:

Thomas R. Cech (as Post Doctoral Fellow)

Rolf Sternglanz (as Graduate Student - Ph.D.)

Ellis J Neufeld (as Technician)
Research:
Other Experience:
1993 Rocky Mountain Biological Laboratory

1993 Sea Education Association (SEA Semester)

Communities:

David Zappulla's Genealogy

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David Zappulla's Publications (15)

Ku can contribute to telomere lengthening in yeast at multiple positions in the telomerase RNP.
Zappulla DC, Goodrich KJ, Arthur JR, Gurski LA, Denham EM, Stellwagen AE, Cech TR

RNA (New York, N.Y.). 2011 Feb;17(2):298-311
Inhibition of yeast telomerase action by the telomeric ssDNA-binding protein, Cdc13p.
Zappulla DC, Roberts JN, Goodrich KJ, Cech TR, Wuttke DS

Nucleic acids research. 2009 Feb;37(2):354-67
A flexible template boundary element in the RNA subunit of fission yeast telomerase.
Box JA, Bunch JT, Zappulla DC, Glynn EF, Baumann P

The Journal of biological chemistry. 2008 Aug 29;283(35):24224-33
RNA as a flexible scaffold for proteins: yeast telomerase and beyond.
Zappulla DC, Cech TR

Cold Spring Harbor symposia on quantitative biology. 2006;71:217-24
Rtt107/Esc4 binds silent chromatin and DNA repair proteins using different BRCT motifs.
Zappulla DC, Maharaj AS, Connelly JJ, Jockusch RA, Sternglanz R

BMC molecular biology. 2006;7:40
A miniature yeast telomerase RNA functions in vivo and reconstitutes activity in vitro.
Zappulla DC, Goodrich K, Cech TR

Nature structural & molecular biology. 2005 Dec;12(12):1072-7
Yeast telomerase RNA: a flexible scaffold for protein subunits.
Zappulla DC, Cech TR

Proceedings of the National Academy of Sciences of the United States of America. 2004 Jul 6;101(27):10024-9
One-hybrid screens at the Saccharomyces cerevisiae HMR locus identify novel transcriptional silencing factors.
Andrulis ED, Zappulla DC, Alexieva-Botcheva K, Evangelista C, Sternglanz R

Genetics. 2004 Jan;166(1):631-5
Esc1, a nuclear periphery protein required for Sir4-based plasmid anchoring and partitioning.
Andrulis ED, Zappulla DC, Ansari A, Perrod S, Laiosa CV, Gartenberg MR, Sternglanz R

Molecular and cellular biology. 2002 Dec;22(23):8292-301
Control of replication timing by a transcriptional silencer.
Zappulla DC, Sternglanz R, Leatherwood J

Current biology : CB. 2002 Jun 4;12(11):869-75
Targeting of the yeast Ty5 retrotransposon to silent chromatin is mediated by interactions between integrase and Sir4p.
Xie W, Gai X, Zhu Y, Zappulla DC, Sternglanz R, Voytas DF

Molecular and cellular biology. 2001 Oct;21(19):6606-14
Prevalence of factor V Leiden in a population of patients with congenital heart disease.
Ong BC, Zimmerman AA, Zappulla DC, Neufeld EJ, Burrows FA

Canadian journal of anaesthesia = Journal canadien d'anesthésie. 1998 Dec;45(12):1176-80
Hair defects and pup loss in mice with targeted deletion of the first cut repeat domain of the Cux/CDP homeoprotein gene.
Tufarelli C, Fujiwara Y, Zappulla DC, Neufeld EJ

Developmental biology. 1998 Aug 1;200(1):69-81
Perinuclear localization of chromatin facilitates transcriptional silencing.
Andrulis ED, Neiman AM, Zappulla DC, Sternglanz R

Nature. 1998 Aug 6;394(6693):592-5
ARMS test for diagnosis of factor VLeiden mutation, a common cause of inherited thrombotic tendency.
Yandava CN, Zappulla DC, Korf BR, Neufeld EJ

Journal of clinical laboratory analysis. 1996;10(6):414-7

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David C Zappulla, Ph.D.

Assistant Professor

David Zappulla's Genealogy

David Zappulla's Publications (15)