Epernicus: Dheepa Balasubramanian, Ph.D.

Dheepa Balasubramanian, Ph.D.

Position:
Post Doctoral Fellow

Case Western Reserve University (Cleveland, OH)
Advisor:
Peter C Scacheri
Degrees:

Ph.D., Biochemistry, University of Illinois at Urbana-Champaign (Urbana, IL)
Past Advisors:
Research:
Skilled scientist with vastf experience in spearheading research projects, applying expertise in RNA Splicing, Cancer biology and chromatin structure and function, successfully training students in genome-wide technologies, effectively collaborating with academic and scientific partners and presenting findings at leading conferences.

The epigenetic causes of gene inactivation in colorectal cancer was demonstrated by gain of DNA hypermethylation, subsequent to loss of active histone mark, H3K4 trimethylation at the non-CpG island promoter containing genes. Interestingly, none of these non-CpG promoters gained any well-known repressive histone marks to contribute to the gene silencing of these genes.

Communities:

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Genomic distribution of CHD7 on chromatin tracks H3K4 methylation patterns.
Schnetz MP, Bartels CF, Shastri K, Balasubramanian D, Zentner GE, Balaji R, Zhang X, Song L, Wang Z, Laframboise T, Crawford GE, Scacheri PC

Genome research. 2009 Apr;19(4):590-601
Functional studies of menin through genetic manipulation of the Men1 homolog in mice.
Balasubramanian D, Scacheri PC

Advances in experimental medicine and biology. 2009;668:105-15

Gene Silencing in Colon cancer (presentation)
Dheepa Balasubramanian

Cleveland; 06/2008
Functional Characterization of SR45 (presentation)
Dheepa Balasubramanian

University of Illinois, Biochemistry Conference; 05/2004
Development silencing and gene knockout analysis (poster)
Dheepa Balasubramanian

Orlando, ASPB Conference; 03/2004
Use of Transgene-Induced Silencing (poster)
Dheepa Balasubramanian

Madison, RNA Conference; 03/2004
Transgene-Induced Silencing (poster)
Dheepa Balasubramanian

Madison; 06/2003

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