Cecilia C Mello, Ph.D.
- Position:
Post Doctoral Fellow
Pathology
Genetics
Stanford University School of Medicine (Stanford, CA)
- Advisor:
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Degrees:
Ph.D., Biology, Biophysics, Johns Hopkins University (Baltimore, MD)B.A., Biology, Brandeis University (Waltham, MA)
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Past Advisors:
Doug Barrick (as Graduate Student - Ph.D.)Andrew Szent-Györgyi (as Undergraduate Student)Eve Marder (as Undergraduate Student)
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Research:
Spectrum of spontaneous and induced mutations
The goal of my project is to characterize the spectra of mutations that arise spontaneously in active genes. By comparing mutation spectra to various functional and structural features of DNA and chromatin, I hope to investigate the connections between genetic activity, context, and the susceptibility or resistance to DNA damage. Carcinogens are known to exert specific effects through their mutagenic spectra, but these are extraordinarily difficult to characterize from epidemiological human data. I have therefore begun to do these experiments in two biologically amenable organisms: Caenorhabditis elegans and Oryzias latipes. These model organisms offer many experimental advantages, including sequenced and annotated genomes.
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Other Experience:
2004-2005 Visiting Assistant Professor, Biology Department, St. Mary's College of Maryland
Cecilia Mello's Genealogy
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