Epernicus: Bobbie Ann Austin, Ph.D.

Bobbie Ann Austin, Ph.D.

Position:
Assistant Director

Science Policy & Programs

Association for Research in Vision and Ophthalmology (Washington, D.C.)
Degrees:

Ph.D., Anatomy and Cell Biology, University of North Dakota School of Medicine & Health Sciences (Grand Forks, ND)
Past Advisors:

Robert A Nussenblatt (as Post Doctoral Fellow)

Daniel J. Carr (as Post Doctoral Fellow)
Research:
Other Experience:
2002-2004 Assistant Professor
Honors:
2008 NEI Director’s Award

2005 Scholarship to attend a course at Marine Biological Laboratory

2004 PI on funded project to incorporate research into undergraduate labs

2002 North Dakota Academy of Science, Roger Denison competition award

2000 Sigma Xi Grant-in-Aid of Research

1996-1998 Howard Hughes Undergraduate Research Apprenticeship

Communities:

Bobbie Austin's Genealogy

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Bobbie Austin's Publications (11)

Biologically active fibronectin fragments stimulate release of MCP-1 and catabolic cytokines from murine retinal pigment epithelium.
Austin BA, Liu B, Li Z, Nussenblatt RB

Investigative ophthalmology & visual science. 2009 Jun;50(6):2896-902
Delivery of Interferon-gamma by an adenovirus vector blocks herpes simplex virus Type 1 reactivation in vitro and in vivo independent of RNase L and double-stranded RNA-dependent protein kinase pathways.
Carr DJ, Austin BA, Halford WP, Stuart PM

Journal of neuroimmunology. 2009 Jan 3;206(1-2):39-43
LX211 (voclosporin) suppresses experimental uveitis and inhibits human T cells.
Cunningham MA, Austin BA, Li Z, Liu B, Yeh S, Chan CC, Anglade E, Velagaleti P, Nussenblatt RB

Investigative ophthalmology & visual science. 2009 Jan;50(1):249-55
Oligoadenylate synthetase/protein kinase R pathways and alphabeta TCR+ T cells are required for adenovirus vector: IFN-gamma inhibition of herpes simplex virus-1 in cornea.
Austin BA, Halford WP, Williams BR, Carr DJ

Journal of immunology (Baltimore, Md. : 1950). 2007 Apr 15;178(8):5166-72
Intact TRL 9 and type I interferon signaling pathways are required to augment HSV-1 induced corneal CXCL9 and CXCL10.
Wuest T, Austin BA, Uematsu S, Thapa M, Akira S, Carr DJ

Journal of neuroimmunology. 2006 Oct;179(1-2):46-52
OAS and PKR are not required for the antiviral effect of Ad:IFN-gamma against acute HSV-1 in primary trigeminal ganglia cultures.
Austin BA, Halford W, Silverman RH, Williams BR, Carr DJ

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research. 2006 Apr;26(4):220-5
Direct application of plasmid DNA containing type I interferon transgenes to vaginal mucosa inhibits HSV-2 mediated mortality.
Austin BA, James CM, Härle P, Carr DJ

Biological procedures online. 2006;8:55-62
Review of the book: Interferons: The Science and Selling of a Miracle Drug
Bobbie Ann Austin

Journal of the History of Medicine and Allied Sciences. 2006;61(3):410-411
Critical role for the oligoadenylate synthetase/RNase L pathway in response to IFN-beta during acute ocular herpes simplex virus type 1 infection.
Austin BA, James C, Silverman RH, Carr DJ

Journal of immunology (Baltimore, Md. : 1950). 2005 Jul 15;175(2):1100-6
Altered collagen fibril formation in the sclera of lumican-deficient mice.
Austin BA, Coulon C, Liu CY, Kao WW, Rada JA

Investigative ophthalmology & visual science. 2002 Jun;43(6):1695-701
Proteoglycan composition in the human sclera during growth and aging.
Rada JA, Achen VR, Penugonda S, Schmidt RW, Mount BA

Investigative ophthalmology & visual science. 2000 Jun;41(7):1639-48

Bobbie Austin's Posters and Presentations (6)

LX211 (ISA247) Suppresses Proliferation of Anti-CD3 Activated Human T-cells and Effectively Treats Experimental Autoimmune Uveitis in Rats (poster)
Austin, B. A., Cunningham, M. A., Li, Z., Liu, B., Chan, C-C, Yeh, S., Anglade, E., Velagalati, P., and Nussenblatt, R. B.

Association for Research in Vision & Ophthalmology, Fort Lauderdale, FL; 04/2008
Model System to Study Interferon Gamma Inhibition of HSV-1 In Vivo (poster)
Austin, B. A., Halford, W. P., and Carr, D. J. J.

International Herpesvirus Workshop, Seattle, WA; 07/2006
Expression proteomics approach to identify downstream effectors of type I interferon-inducible pathways that are potential therapeutic targets against ocular HSV-1. (poster)
Austin, B. A., Haniu, H., Matsumoto, H., and Carr, D. J. J.

Molecular Pathogenesis of Infectious and Inflammatory Eye Disease Research, Cleveland, OH; 09/2005
Tyrosine Sulfation of Scleral Lumican (poster)
Austin, B. A., Roughley, P.J., and Rada, J. A.

American Society for Cell Biology, Washington DC; 12/2001
Alternative Forms of Lumican Core Protein are Present in the Human Sclera (presentation)
Austin, B. A., Roughley, P.J., and Rada, J. A.

. Proceedings of the VIII International Conference on Myopia, Boston, MA; 07/2000
Corneal Keratan Sulfate Proteoglycan (Lumican) is present in the Human Sclera as Both Proteoglycan and Glycoprotein Forms (poster)
Mount, B. A., Roughley, P. J., and Rada, J. A.

Association for Research in Vision and Ophthalmology, Fort Lauderdale, FL; 05/1999

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