Epernicus: Anthony Percival-Smith, Ph.D.

Anthony Percival-Smith, Ph.D.

Position:
Associate Professor

Biology

University of Western Ontario (London, Canada)
Degrees:

Ph.D., Biochemistry, University of Toronto (Toronto, Canada)

B.Sc., Biochemistry, University of British Columbia (Vancouver, Canada)
Past Advisors:

Henry M Krause (as Post Doctoral Fellow)

Walter J. Gehring (as Post Doctoral Fellow)

Jacqueline Segall (as Graduate Student - Ph.D.)
Research:
Homeotic (HOX) protein function in the development of Drosophila melanogaster

Communities:

Anthony Percival-Smith's Genealogy

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Anthony Percival-Smith's Publications (21)

Analysis of the sequence and phenotype of Drosophila Sex combs reduced alleles reveals potential functions of conserved protein motifs of the Sex combs reduced protein.
Sivanantharajah L, Percival-Smith A

Genetics. 2009 May;182(1):191-203
Non-requirement of a regulatory subunit of Protein Phosphatase 2A, PP2A-B', for activation of Sex comb reduced activity in Drosophila melanogaster.
Moazzen H, Rosenfeld R, Percival-Smith A

Mechanisms of development. 2009 Aug-Sep;126(8-9):605-10
Tarsus determination in Drosophila melanogaster.
Percival-Smith A, Teft WA, Barta JL

Genome / National Research Council Canada = Génome / Conseil national de recherches Canada. 2005 Aug;48(4):712-21
Analysis of Drosophila proboscipedia mutant alleles.
Tayyab I, Hallahan HM, Percival-Smith A

Genome / National Research Council Canada = Génome / Conseil national de recherches Canada. 2004 Jun;47(3):600-9
A novel transmembrane protein recruits numb to the plasma membrane during asymmetric cell division.
Qin H, Percival-Smith A, Li C, Jia CY, Gloor G, Li SS

The Journal of biological chemistry. 2004 Mar 19;279(12):11304-12
Low-level ectopic expression of Fushi tarazu in Drosophila melanogaster results in ftz(Ual/Rpl)-like phenotypes and rescues ftz phenotypes.
Argiropoulos B, Ho J, Blachuta BJ, Tayyab I, Percival-Smith A

Mechanisms of development. 2003 Dec;120(12):1443-53
FTZ-Factor1 and Fushi tarazu interact via conserved nuclear receptor and coactivator motifs.
Schwartz CJ, Sampson HM, Hlousek D, Percival-Smith A, Copeland JW, Simmonds AJ, Krause HM

The EMBO journal. 2001 Feb 1;20(3):510-9
Analysis of murine HOXA-2 activity in Drosophila melanogaster.
Percival-Smith A, Bondy JA

Developmental genetics. 1999;24(3-4):336-44
Analysis in Drosophila melanogaster of the interaction between sex combs reduced and extradenticle activity in the determination of tarsus and arista identity.
Percival-Smith A, Hayden DJ

Genetics. 1998 Sep;150(1):189-98
Genetic characterization of the role of the two HOX proteins, Proboscipedia and Sex Combs Reduced, in determination of adult antennal, tarsal, maxillary palp and proboscis identities in Drosophila melanogaster.
Percival-Smith A, Weber J, Gilfoyle E, Wilson P

Development (Cambridge, England). 1997 Dec;124(24):5049-62
The nuclear receptor homologue Ftz-F1 and the homeodomain protein Ftz are mutually dependent cofactors.
Guichet A, Copeland JW, Erdélyi M, Hlousek D, Závorszky P, Ho J, Brown S, Percival-Smith A, Krause HM, Ephrussi A

Nature. 1997 Feb 6;385(6616):548-52
Genetic characterization of the homeodomain-independent activity of the Drosophila fushi tarazu gene product.
Hyduk D, Percival-Smith A

Genetics. 1996 Feb;142(2):481-92
Homeodomain-independent activity of the fushi tarazu polypeptide in Drosophila embryos.
Fitzpatrick VD, Percival-Smith A, Ingles CJ, Krause HM

Nature. 1992 Apr 16;356(6370):610-2
Similarities between the homeodomain and the Hin recombinase DNA-binding domain.
Affolter M, Percival-Smith A, Müller M, Billeter M, Qian YQ, Otting G, Wüthrich K, Gehring WJ

Cell. 1991 Mar 8;64(5):879-80
The interaction with DNA of wild-type and mutant fushi tarazu homeodomains.
Percival-Smith A, Müller M, Affolter M, Gehring WJ

The EMBO journal. 1990 Dec;9(12):3967-74
The structure of the homeodomain and its functional implications.
Gehring WJ, Müller M, Affolter M, Percival-Smith A, Billeter M, Qian YQ, Otting G, Wüthrich K

Trends in genetics : TIG. 1990 Oct;6(10):323-9
DNA binding properties of the purified Antennapedia homeodomain.
Affolter M, Percival-Smith A, Müller M, Leupin W, Gehring WJ

Proceedings of the National Academy of Sciences of the United States of America. 1990 Jun;87(11):4093-7
Increased copy number of the 5' end of the SPS2 gene inhibits sporulation of Saccharomyces cerevisiae.
Percival-Smith A, Segall J

Molecular and cellular biology. 1987 Jul;7(7):2484-90
Characterization and mutational analysis of a cluster of three genes expressed preferentially during sporulation of Saccharomyces cerevisiae.
Percival-Smith A, Segall J

Molecular and cellular biology. 1986 Jul;6(7):2443-51
Glucagon inhibits phosphatidylcholine biosynthesis via the CDP-choline and transmethylation pathways in cultured rat hepatocytes.
Pelech SL, Pritchard PH, Sommerman EF, Percival-Smith A, Vance DE

Canadian journal of biochemistry and cell biology = Revue canadienne de biochimie et biologie cellulaire. 1984 Apr;62(4):196-202
Isolation of DNA sequences preferentially expressed during sporulation in Saccharomyces cerevisiae.
Percival-Smith A, Segall J

Molecular and cellular biology. 1984 Jan;4(1):142-50

One Figure

Genetic model proposed for Sex combs reduced activity.

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