Epernicus: Andrew K Vershon, Ph.D.

Andrew K Vershon, Ph.D.

Position:
Professor

Molecular Biology & Biochemistry

Waksman Institute

Rutgers University (New Brunswick, NJ)
Degrees:

Ph.D., Biology, Massachusetts Institute of Technology (Cambridge, MA)

B.A., Biology, Bennington College
Past Advisors:

Alexander Johnson (as Post Doctoral Fellow)

Robert T. Sauer (as Graduate Student - Ph.D.)
Research:
Other Experience:
1980-1981 Technician - University of Massachusetts Medical School

1979-1981 Technician - Hoffman La Roche

Communities:

Andrew Vershon's Genealogy

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Andrew Vershon's Publications (49)

Swapping the gene-specific and regional silencing specificities of the Hst1 and Sir2 histone deacetylases.
Mead J, McCord R, Youngster L, Sharma M, Gartenberg MR, Vershon AK

Molecular and cellular biology. 2007 Apr;27(7):2466-75
N-terminal arm of Mcm1 is required for transcription of a subset of genes involved in maintenance of the cell wall.
Abraham DS, Vershon AK

Eukaryotic cell. 2005 Nov;4(11):1808-19
Analysis of the meiotic role of the mitochondrial ribosomal proteins Mrps17 and Mrpl37 in Saccharomyces cerevisiae.
Hanlon SE, Xu Z, Norris DN, Vershon AK

Yeast (Chichester, England). 2004 Nov;21(15):1241-52
Combined analysis of expression data and transcription factor binding sites in the yeast genome.
Nagaraj VH, O'Flanagan RA, Bruning AR, Mathias JR, Vershon AK, Sengupta AM

BMC genomics. 2004 Aug 26;5(1):59
Alpha1-induced DNA bending is required for transcriptional activation by the Mcm1-alpha1 complex.
Carr EA, Mead J, Vershon AK

Nucleic acids research. 2004;32(8):2298-305
Characterization of critical interactions between Ndt80 and MSE DNA defining a novel family of Ig-fold transcription factors.
Fingerman IM, Sutphen K, Montano SP, Georgiadis MM, Vershon AK

Nucleic acids research. 2004;32(9):2947-56
Repression of the yeast HO gene by the MATalpha2 and MATa1 homeodomain proteins.
Mathias JR, Hanlon SE, O'Flanagan RA, Sengupta AM, Vershon AK

Nucleic acids research. 2004;32(22):6469-78
Sfp1 plays a key role in yeast ribosome biogenesis.
Fingerman I, Nagaraj V, Norris D, Vershon AK

Eukaryotic cell. 2003 Oct;2(5):1061-8
Depletion of H2A-H2B dimers in Saccharomyces cerevisiae triggers meiotic arrest by reducing IME1 expression and activating the BUB2-dependent branch of the spindle checkpoint.
Hanlon SE, Norris DN, Vershon AK

Genetics. 2003 Aug;164(4):1333-44
Sum1 and Ndt80 proteins compete for binding to middle sporulation element sequences that control meiotic gene expression.
Pierce M, Benjamin KR, Montano SP, Georgiadis MM, Winter E, Vershon AK

Molecular and cellular biology. 2003 Jul;23(14):4814-25
Rfm1, a novel tethering factor required to recruit the Hst1 histone deacetylase for repression of middle sporulation genes.
McCord R, Pierce M, Xie J, Wonkatal S, Mickel C, Vershon AK

Molecular and cellular biology. 2003 Mar;23(6):2009-16
Crystallographic studies of a novel DNA-binding domain from the yeast transcriptional activator Ndt80.
Montano SP, Pierce M, Coté ML, Vershon AK, Georgiadis MM

Acta crystallographica. Section D, Biological crystallography. 2002 Dec;58(Pt 12):2127-30
Crystal structure of the DNA-binding domain from Ndt80, a transcriptional activator required for meiosis in yeast.
Montano SP, Coté ML, Fingerman I, Pierce M, Vershon AK, Georgiadis MM

Proceedings of the National Academy of Sciences of the United States of America. 2002 Oct 29;99(22):14041-6
Swapping functional specificity of a MADS box protein: residues required for Arg80 regulation of arginine metabolism.
Jamai A, Dubois E, Vershon AK, Messenguy F

Molecular and cellular biology. 2002 Aug;22(16):5741-52
Interactions of the Mcm1 MADS box protein with cofactors that regulate mating in yeast.
Mead J, Bruning AR, Gill MK, Steiner AM, Acton TB, Vershon AK

Molecular and cellular biology. 2002 Jul;22(13):4607-21
Structural and thermodynamic characterization of the DNA binding properties of a triple alanine mutant of MATalpha2.
Ke A, Mathias JR, Vershon AK, Wolberger C

Structure (London, England : 1993). 2002 Jul;10(7):961-71
Engineered improvements in DNA-binding function of the MATa1 homeodomain reveal structural changes involved in combinatorial control.
Hart B, Mathias JR, Ott D, McNaughton L, Anderson JS, Vershon AK, Baxter SM

Journal of molecular biology. 2002 Feb 15;316(2):247-56
Altering the DNA-binding specificity of the yeast Matalpha 2 homeodomain protein.
Mathias JR, Zhong H, Jin Y, Vershon AK

The Journal of biological chemistry. 2001 Aug 31;276(35):32696-703
Localization and signaling of G(beta) subunit Ste4p are controlled by a-factor receptor and the a-specific protein Asg7p.
Kim J, Bortz E, Zhong H, Leeuw T, Leberer E, Vershon AK, Hirsch JP

Molecular and cellular biology. 2000 Dec;20(23):8826-35
Transcriptional regulation of meiosis in yeast.
Vershon AK, Pierce M

Current opinion in cell biology. 2000 Jun;12(3):334-9
Scanning mutagenesis of Mcm1: residues required for DNA binding, DNA bending, and transcriptional activation by a MADS-box protein.
Acton TB, Mead J, Steiner AM, Vershon AK

Molecular and cellular biology. 2000 Jan;20(1):1-11
Identification of target sites of the alpha2-Mcm1 repressor complex in the yeast genome.
Zhong H, McCord R, Vershon AK

Genome research. 1999 Nov;9(11):1040-7
Sum1 and Hst1 repress middle sporulation-specific gene expression during mitosis in Saccharomyces cerevisiae.
Xie J, Pierce M, Gailus-Durner V, Wagner M, Winter E, Vershon AK

The EMBO journal. 1999 Nov 15;18(22):6448-54
The yeast a1 and alpha2 homeodomain proteins do not contribute equally to heterodimeric DNA binding.
Jin Y, Zhong H, Vershon AK

Molecular and cellular biology. 1999 Jan;19(1):585-93
Crystal structure of the MATa1/MATalpha2 homeodomain heterodimer in complex with DNA containing an A-tract.
Li T, Jin Y, Vershon AK, Wolberger C

Nucleic acids research. 1998 Dec 15;26(24):5707-18

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Andrew K Vershon, Ph.D.

Professor

Andrew Vershon's Genealogy

Andrew Vershon's Publications (49)