Amber K O'Connor

Amber K O'Connor, B.S.

(Ph.D. in progress)
  • Position:
    Graduate Student - Ph.D.

    Cell Biology

    CMB

    University of Alabama at Birmingham (Birmingham, AL)

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  • Advisor:

    Bradley K. Yoder

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  • Degrees:
     
    Ph.D. (in progress), Cell Biology, University of Alabama at Birmingham (Birmingham, AL)
     
    B.S., Microbiology, Arizona State University (Tempe, AZ)
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  • Past Advisors:
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  • Research:
    The role of the Primary Cilium in Hedgehog Signaling.

    My research focuses on the role of the primary cilium in Hedgehog signaling. Primary cilia are solitary microtubule based extensions found on nearly every cell in the mammalian body. Mutations in cilia genes lead to multiple phenotypes including polycystic kidney disease, blindness, deafness, mental retardation, obesity, polydactyly, and cystic pancreas and liver; however systemic ablation of cilia throughout development is lethal. Some of the phenotypes observed in cilia mutants; polydactyly and alterations in neural tube patterning, have led to the discovery that primary cilia are required for proper hedgehog signaling. My project is to determine what role in hedgehog signaling the cilium plays using the limb bud as a model system.

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  • Other Experience:

    2006 Internship

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  • Honors:

    2006 Summa cum laude

Life Sciences
Communities:

Amber O'Connor's Genealogy

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Amber O'Connor's Publications (2)



Amber O'Connor's Posters and Presentations (3)

  • Varied roles for Primary cilia on Shh producing and responding cells of the limb bud. (poster)

    O’Connor A.K., C.J. Haycraft, and B.K. Yoder

    American Society for Cell Biology, San Diego CA; 12/2009
  • Primary Cilia function in Shh producing and responding cells of the limb bud (poster)

    O’Connor, A.K., Haycraft C.J., Berbari N.F., Verheyden V., Sun X., and Yoder B.K

    ASCB; 12/2008
  • β-COP depletion reveals roles for COP-I in organellar compartmentalization and transport of Ceveolin-1 (poster)

    Styers, M.L., A.K. O’Connor, R. Grabski, E. Cormet-Boyaka, and E. Sztul

    ASCB; 12/2007

One Figure

One Figure for Amber K O'Connor

Skeletal prep of a conditional cilia mutant forelimb


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