Epernicus: Akila Jayaraman, M.Sc.

Akila Jayaraman, M.Sc.

(Ph.D. in progress)

Position:
Graduate Student - Ph.D.

Biological Engineering

Massachusetts Institute of Technology (Cambridge, MA)
Advisor:
Ram Sasisekharan
Degrees:

Ph.D. (in progress), Biological Engineering, Massachusetts Institute of Technology (Cambridge, MA)

M.Sc., Biotechnology, University of Madras (Chennai, India)

B.Sc., Biochemistry and Nutrition (Double Major), Avinashilingam University (Coimbatore, India)
Past Advisors:

Arun Balakrishnan (as Senior Scientist)

T. S. Lokeswari (as Visiting Student)

Late Dr. P. V. Sundaram (as Graduate Student - Masters)
Research:
My research aims on understanding the role of Influenza A virus hemagglutinin - cell surface glycan receptor interaction in viral pathogenesis
Other Experience:
2003-2004 Research Scientist in Center for Biotechnology, Anna University

2002-2003 Research Fellow, Center for Biotechnology, SPIC, India

Communities:

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A Single Base-Pair Change in 2009 H1N1 Hemagglutinin Increases Human Receptor Affinity and Leads to Efficient Airborne Viral Transmission in Ferrets.
Jayaraman A, Pappas C, Raman R, Belser JA, Viswanathan K, Shriver Z, Tumpey TM, Sasisekharan R

PloS one. 2011;6(3):e17616
Transmission and Pathogenesis of Swine-Origin 2009 A(H1N1) Influenza Viruses in Ferrets and Mice.
Maines TR, Jayaraman A, Belser JA, Wadford DA, Pappas C, Zeng H, Gustin KM, Pearce MB, Viswanathan K, Shriver ZH, Raman R, Cox NJ, Sasisekharan R, Katz JM, Tumpey TM

Science (New York, N.Y.). 2009 Jul 2
Hemagglutinin Receptor Binding Avidity Drives Influenza A virus Antigenic Drift
Scott E Hensley, Suman R Das, Adam L Bailey, Loren M Schmidt, Heather D Hickman, Akila Jayaraman, Karthik Viswanathan, Rahul Raman, Ram Sasisekharan, Jack R Bennink, Jonathan W Yewdell

Science. 2009;326:734-736

Exploiting Glycan Binding Specificity of Lectins to Target Host Receptors in Disease (presentation)
Akila Jayaraman

Koch Institute Fall Retreat, Hyannis, MA; 10/2010
Hemagglutinin Receptor Binding Avidity drives Influenza A virus antigenic drift (poster)
Akila Jayaraman, Karthik Viswanathan, Rahul Raman and Ram Sasisekharan

Biological Engineering Retreat 2010, Newport, Rhode Island; 03/2010
Glycan Receptor-Binding Specificity in Human Adaptation of Influenza A virus Hemagglutinin (poster)
Akila Jayaraman, Karthik Viswanathan, Rahul Raman, Zachary Shriver, S Raguram, V Sasisekharan, Ram Sasisekharan

20th International Symposium on Glycoconjugates, San Juan, Puerto Rico; 12/2009
Decoding Dynamic Structure-Function Relationships of Glycans (presentation)
Akila Jayaraman

Koch Institute for Integrated Cancer Research Retreat ; 10/2009
Decoding Glycans In DIseases (poster)
Akila Jayaraman, Xiaoying (Carol) Koh, Venkataramanan Soundararajan, Ram Sasisekharan

Koch Institute for Integrated Cancer Research Retreat ; 10/2009

Human tracheal and Alveolar tissue binding of Swine Flu HA (CA/04)

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